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克雷沃斯特与勒马里：关于传统用途、植物学、植物化学和药理学的全面综述

Crevost & Lemarié: a comprehensive review on traditional uses, botany, phytochemistry, and pharmacology.

作者信息

Yang Siyuan, Xue Yafu, Chen Daju, Wang Zhengtao

机构信息

The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicine, The MOE Key Laboratory for Standardization of Chinese Medicines and Shanghai Key Laboratory of Compound Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203 China.

School of Pharmacy, China Pharmaceutical University, Nanjing, 211198 Jiangsu China.

出版信息

Phytochem Rev. 2022;21(5):1487-1521. doi: 10.1007/s11101-021-09793-x. Epub 2022 Jan 10.

DOI:10.1007/s11101-021-09793-x
PMID:35035319
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8743105/
Abstract

UNLABELLED

Tsaoko Fructus, the dried ripe fruit of Crevost & Lemarié, is used as both medicinal material and food additive. This review summarized the traditional uses, botany, phytochemistry, and pharmacological progress on Tsaoko Fructus. One classical prescription and the other 11 representative prescriptions containing Tsaoko Fructus were reviewed. The indications of these prescriptions are major in treating spleen and stomach disorders and epidemic febrile diseases including malaria. At least 209 compounds have been isolated and identified from Tsaoko Fructus, most of which belong to terpenoids, phenylpropanoids, and organic acids. Essential oil, crude extract, and some compounds were observed to have pharmacological activities such as anti-biotics, anti-inflammation, antioxidant, mostly via in vitro experiments. However, the mechanism of its medicinal uses remains unclear. This review provides a comprehensive understanding of Tsaoko Fructus, which will be beneficial to exploring the mechanism and potential medicinal applications of Tsaoko Fructus, as well as developing a rational quality control system for Tsaoko Fructus as a medicinal material in the future.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s11101-021-09793-x.

摘要

未标注

草果是姜科豆蔻属植物草果的干燥成熟果实，用作药材和食品添加剂。本综述总结了草果的传统用途、植物学、植物化学和药理学研究进展。回顾了1首经典方剂和其他11首含草果的代表性方剂。这些方剂的适应证主要为治疗脾胃病症和包括疟疾在内的温热病。从草果中已分离鉴定出至少209种化合物，其中大多数属于萜类、苯丙素类和有机酸类。精油、粗提取物和一些化合物经体外实验观察到具有抗菌、抗炎、抗氧化等药理活性。然而，其药用机制尚不清楚。本综述为全面了解草果提供了参考，有助于探索草果的作用机制和潜在药用价值，以及未来制定合理的草果药材质量控制体系。

补充信息

网络版包含可在10.1007/s11101-021-09793-x获取的补充材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/5ad667811363/11101_2021_9793_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/9ab3abea5a4b/11101_2021_9793_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/4fc910ca1361/11101_2021_9793_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/3a9b5c8dd1f7/11101_2021_9793_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/5663442856bd/11101_2021_9793_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/de5989d73977/11101_2021_9793_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/7ce1f6a4dba6/11101_2021_9793_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/863d4c9dba83/11101_2021_9793_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/5ad667811363/11101_2021_9793_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/9ab3abea5a4b/11101_2021_9793_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/4fc910ca1361/11101_2021_9793_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/3a9b5c8dd1f7/11101_2021_9793_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/5663442856bd/11101_2021_9793_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/de5989d73977/11101_2021_9793_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/7ce1f6a4dba6/11101_2021_9793_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/863d4c9dba83/11101_2021_9793_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/8743105/5ad667811363/11101_2021_9793_Fig8_HTML.jpg

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