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血液透析患者检测重复性的测量时间影响。

Impact of measurement timing on reproducibility of testing among haemodialysis patients.

机构信息

Nephrology Department, Hospital de Terrassa, Consorci Sanitari de Terrassa, Crta Torrebonica s/n, 08227, Terrassa, Spain.

Nursing Department, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain.

出版信息

Sci Rep. 2022 Jan 19;12(1):1004. doi: 10.1038/s41598-021-02526-2.

DOI:10.1038/s41598-021-02526-2
PMID:35046421
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8770792/
Abstract

Accurate evaluation of physical function in patients undergoing haemodialysis is crucial in the analysis of the impact of exercise programs in this population. The aim of this study was to evaluate the reproducibility of several physical functional tests, depending on the timing of their implementation (before the HD session vs. non-HD days). This is a prospective, non-experimental, descriptive study. Thirty patients in haemodialysis were evaluated twice, 1 week apart. The test session was performed before the haemodialysis session started and a retest was performed in non-dialysis day. The testing battery included the short physical performance battery, sit-to-stand tests, 6 min walk test, one-leg stand test, timed up and go, and handgrip strength with and without forearm support. The intra-rater reproducibility was determined by the intraclass correlation coefficients and the agreement was assessed by Bland-Altman analysis. The intraclass correlation coefficients values ranged from 0.86 to 0.96, so that all tests showed good to very good relative reliability. The mean differences between trials of sit to stand 10 and 60, timed up and go and all the handgrip tests were close to zero, indicating no systematic differences between trials. Large range of values between trials was observed for the 6 min walk test, gait speed, one-leg stand test and short physical performance battery, indicating a systematic bias for these four tests. In conclusion,  the sit to stand 10 and 60, timed up and go and handgrip tests had good to excellent test-retest reliability in measuring physical function in different dialysis days of patients undertaking haemodialysis. The minimal detectable change values are provided for this population. Bias were found for the 6 min walk test, gait speed, Short physical performance battery or one-leg stand test when the testing day changed.

摘要

准确评估血液透析患者的身体功能对于分析运动方案对该人群的影响至关重要。本研究旨在评估几种身体功能测试的可重复性,具体取决于其实施时间(在血液透析治疗前与非血液透析日)。这是一项前瞻性、非实验性、描述性研究。30 名血液透析患者在相隔 1 周的时间内接受了两次评估。测试在血液透析治疗开始前进行,然后在非透析日进行复测。测试包括短体适能测试、坐站测试、6 分钟步行测试、单腿站立测试、计时起立行走测试和握力测试(有和无前臂支撑)。组内可靠性通过组内相关系数确定,一致性通过 Bland-Altman 分析评估。组内相关系数值范围为 0.86 至 0.96,表明所有测试均具有良好至非常好的相对可靠性。坐站 10 次和 60 次、计时起立行走测试和所有握力测试的试验间差异均值接近零,表明试验间无系统差异。6 分钟步行测试、步态速度、单腿站立测试和短体适能测试的试验间值范围较大,表明这四个测试存在系统偏差。总之,坐站 10 次和 60 次、计时起立行走测试和握力测试在测量不同血液透析日患者的身体功能时具有良好至优秀的重测可靠性。为该人群提供了最小可检测变化值。当测试日发生变化时,6 分钟步行测试、步态速度、短体适能测试或单腿站立测试的偏差较大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/f8b8c5559447/41598_2021_2526_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/74e516d867ba/41598_2021_2526_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/387f9dae860a/41598_2021_2526_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/d99aa7433961/41598_2021_2526_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/a9522a68d8f6/41598_2021_2526_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/f8b8c5559447/41598_2021_2526_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/74e516d867ba/41598_2021_2526_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/387f9dae860a/41598_2021_2526_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/1671b9360e38/41598_2021_2526_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/d99aa7433961/41598_2021_2526_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/a9522a68d8f6/41598_2021_2526_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5db/8770792/f8b8c5559447/41598_2021_2526_Fig6_HTML.jpg

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