The University of Texas Rio Grande Valley School of Medicine, Edinburg, TX 78541, USA.
Section of Plastic Surgery, Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03766, USA.
Int J Mol Sci. 2022 Jan 7;23(2):644. doi: 10.3390/ijms23020644.
Currently, many different techniques exist for the surgical repair of peripheral nerves. The degree of injury dictates the repair and, depending on the defect or injury of the peripheral nerve, plastic surgeons can perform nerve repairs, grafts, and transfers. All the previously listed techniques are routinely performed in human patients, but a novel addition to these peripheral nerve surgeries involves concomitant fat grafting to the repair site at the time of surgery. Fat grafting provides adipose-derived stem cells to the injury site. Though fat grafting is performed as an adjunct to some peripheral nerve surgeries, there is no clear evidence as to which procedures have improved outcomes resultant from concomitant fat grafting. This review explores the evidence presented in various animal studies regarding outcomes of fat grafting at the time of various types of peripheral nerve surgery.
目前,有许多不同的技术可用于外周神经的外科修复。损伤的程度决定了修复方式,根据外周神经的缺损或损伤,整形外科医生可以进行神经修复、移植和转移。所有之前列出的技术都在人类患者中常规进行,但这些外周神经手术的一个新的补充是在手术时同时向修复部位进行脂肪移植。脂肪移植为损伤部位提供脂肪来源的干细胞。尽管脂肪移植作为一些外周神经手术的辅助手段,但没有明确的证据表明哪些手术可以改善同时进行脂肪移植的结果。本综述探讨了各种动物研究中提出的证据,这些研究涉及在各种类型的外周神经手术时进行脂肪移植的结果。