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Regulation of immune response to SRBC: suppressor cell activity induced by soluble fraction of antigen.对绵羊红细胞免疫反应的调节：抗原可溶性部分诱导的抑制细胞活性。
Immunology. 1978 May;34(5):791-9.
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本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Studies on cyclophosphamide-induced tolerance to sheep erythrocytes.环磷酰胺诱导对绵羊红细胞耐受性的研究。
J Exp Med. 1967 May 1;125(5):833-45. doi: 10.1084/jem.125.5.833.
3
Thymus-marrow cell combinations. Synergism in antibody production.胸腺-骨髓细胞组合。抗体产生中的协同作用。
Proc Soc Exp Biol Med. 1966 Aug-Sep;122(4):1167-71. doi: 10.3181/00379727-122-31353.
4
Competition of 19S and 7S antigen receptors in the regulation of the primary immune response.19S和7S抗原受体在初次免疫反应调节中的竞争
J Exp Med. 1968 Jul 1;128(1):133-52. doi: 10.1084/jem.128.1.133.
5
The requirement for macrophages in the in vitro immune response.体外免疫反应中对巨噬细胞的需求。
Cell Immunol. 1971 Oct;2(5):399-410. doi: 10.1016/0008-8749(71)90051-7.
6
Regulation of the immune response. I. "Accelerated" response induced by suboptimal antigen concentration.免疫反应的调节。I. 次优抗原浓度诱导的“加速”反应。
Cell Immunol. 1972 Jan;3(1):62-9. doi: 10.1016/0008-8749(72)90226-2.
7
Regulation of the immune response. II. Transfer of the "accelerated" response.免疫反应的调节。II. “加速”反应的转移。
Cell Immunol. 1972 Jan;3(1):70-7. doi: 10.1016/0008-8749(72)90227-4.
8
Use of an antiglobulin serum to detect cells producing antibody with low haemolytic efficiency.使用抗球蛋白血清检测产生溶血效率低的抗体的细胞。
Nature. 1965 Nov 27;208(5013):859-61. doi: 10.1038/208859a0.
9
Infectious immunological tolerance.感染性免疫耐受
Immunology. 1971 Dec;21(6):903-14.
10
The mechanism of antibody-induced stimulation and inhibition of the immune response.抗体诱导的免疫反应刺激与抑制机制。
J Immunol. 1971 Apr;106(4):951-5.

对绵羊红细胞免疫反应的调节：抗原可溶性部分诱导的抑制细胞活性。

Regulation of immune response to SRBC: suppressor cell activity induced by soluble fraction of antigen.

作者信息

Lukić M L, Janezić A, Popesković L

出版信息

Immunology. 1978 May;34(5):791-9.

PMID:350759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1457200/
Abstract

Water soluble fraction (SF) of SRBC was obtained by hypotonic lysis and ultracentrifugation. SF was found to induce very weak SRBC-specific antibody response in mice. Pretreatment with SF accelerated direct PFC response to SRBC and accelerated and suppressed indirect PFC response. Spleen cells from mice treated with SF exhibited enhanced response to SRBC after transfer in irradiated recipients. The transfer of spleen cells from mice treated with SF to normal non-irradiated mice markedly suppressed the recipients' PFC responses to SRBC. The observed suppressive effect is interpreted as a consequence of suppressor cell activity.

摘要

通过低渗裂解和超速离心获得SRBC的水溶性部分（SF）。发现SF在小鼠中诱导非常微弱的SRBC特异性抗体反应。用SF预处理可加速对SRBC的直接PFC反应，并加速和抑制间接PFC反应。用SF处理的小鼠的脾细胞在转移到受辐照受体后对SRBC表现出增强的反应。将用SF处理的小鼠的脾细胞转移到正常未辐照的小鼠中，显著抑制了受体对SRBC的PFC反应。观察到的抑制作用被解释为抑制细胞活性的结果。