Department of Clinical Psychology, University of Graz, Universitätsplatz 2/DG, 8010, Graz, Austria.
BioTechMed, Graz, Austria.
Sci Rep. 2022 Jan 25;12(1):1327. doi: 10.1038/s41598-022-05407-4.
Research has discovered structural differences in the brains of people with different personality types. In the present voxel-based morphometry study we focused on the association between disgust propensity (DP: the temporally stable tendency to experience disgust across different situations) and grey matter volume (GMV) in regions of interest [insula, orbitofrontal cortex (OFC), basal ganglia]. We collected structural brain scans from 498 healthy individuals (352 females, 146 males; mean age = 27 years). Regression analyses were performed to test the association between three domains of DP (core, animal-reminder, contamination) and GMV. We observed negative correlations between animal-reminder DP and the volume of the insula, and contamination DP and OFC volume. Animal-reminder DP correlated positively with GMV in the basal ganglia (putamen). This study identified weak correlations between local brain volume and disgust propensity. The association between DP and insula volume concerned the posterior insula and was in the opposite of the expected direction. The findings of this study are inconsistent with the concept of the anterior insula as a region that specifically mediates DP.
研究发现，不同人格类型的人的大脑存在结构差异。在目前的基于体素的形态计量学研究中，我们专注于厌恶倾向（DP：在不同情况下经历厌恶的暂时稳定倾向）与感兴趣区域（岛叶、眶额皮质（OFC）、基底神经节）的灰质体积（GMV）之间的关联。我们从 498 名健康个体（352 名女性，146 名男性；平均年龄 27 岁）中收集了结构脑扫描。回归分析用于测试 DP 的三个领域（核心、动物提醒、污染）与 GMV 之间的关联。我们观察到动物提醒 DP 与岛叶体积呈负相关，污染 DP 与 OFC 体积呈负相关。动物提醒 DP 与基底神经节（壳核）的 GMV 呈正相关。这项研究发现局部脑体积与厌恶倾向之间存在微弱的相关性。DP 与岛叶体积的关联涉及后岛叶，与预期方向相反。这项研究的结果与前岛叶作为专门调节 DP 的区域的概念不一致。
