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日本大阪地区生殖年龄段孕妇和非孕妇的 COVID-19 特征和结局。

Characteristics and Outcomes of COVID-19 in Reproductive-Aged Pregnant and Nonpregnant Women in Osaka, Japan.

机构信息

Environmental Medicine and Population Sciences, Department of Social Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.

Environmental Medicine and Population Sciences, Department of Social Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.

出版信息

Int J Infect Dis. 2022 Apr;117:195-200. doi: 10.1016/j.ijid.2022.01.054. Epub 2022 Jan 29.

DOI:10.1016/j.ijid.2022.01.054
PMID:35104668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8800534/
Abstract

OBJECTIVE

To describe the clinical characteristics and outcomes of reproductive-aged female patients with coronavirus disease 2019 (COVID-19).

METHODS

We conducted a retrospective study of female patients aged 10-49 years, diagnosed with COVID-19 in Osaka, Japan, between January and November 2020. We assessed their epidemiological and clinical characteristics according to their pregnancy status.

RESULTS

A total of 4,156 patients were enrolled, of whom 29 (0.7%) were pregnant. Most patients exhibited mild symptoms, and 10.8% of the cases were asymptomatic. No moderate or severe cases were observed in pregnant women, whereas only 0.1% of the nonpregnant women had severe disease at diagnosis. No clusters were observed in the pregnant patients; however, most acquired the infection from a family member. Of the 29 pregnant women, 22 (75.9%) were hospitalized; whereas among the nonpregnant women, 579 (14.0%) were hospitalized (p < 0.001). No patients were admitted to the intensive care unit, and there were no deaths among women aged 10-49 years.

CONCLUSIONS

Pregnant women accounted for 0.7% of the total cases of COVID-19 among women aged 10-49 years. Pregnant women were more likely to be hospitalized but generally had mild disease.

摘要

目的

描述生育年龄女性 2019 冠状病毒病(COVID-19)患者的临床特征和结局。

方法

我们对 2020 年 1 月至 11 月在日本大阪诊断为 COVID-19 的 10-49 岁育龄期女性患者进行了回顾性研究。我们根据其妊娠状态评估了她们的流行病学和临床特征。

结果

共纳入 4156 例患者,其中 29 例(0.7%)妊娠。大多数患者表现为轻症,10.8%的病例为无症状。妊娠妇女中未观察到中重度病例,而诊断时仅有 0.1%的非妊娠妇女患有重症疾病。妊娠患者中未观察到聚集性病例;然而,大多数患者是从家庭成员那里感染的。29 例妊娠妇女中,22 例(75.9%)住院;而非妊娠妇女中,579 例(14.0%)住院(p<0.001)。没有患者住进重症监护病房,10-49 岁女性中没有死亡病例。

结论

妊娠妇女占 10-49 岁育龄期 COVID-19 总病例的 0.7%。妊娠妇女更有可能住院,但总体上疾病较轻。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba30/8800534/06970fbde801/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba30/8800534/7c760ecf6b57/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba30/8800534/06970fbde801/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba30/8800534/7c760ecf6b57/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba30/8800534/06970fbde801/gr2_lrg.jpg

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