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三级医疗中心多囊卵巢综合征(PCOS)患者皮肤表现与体重指数(BMI)的相关性:一项观察性研究。

Correlation of Cutaneous Manifestations With Body Mass Index (BMI) in Polycystic Ovary Syndrome (PCOS) Patients in a Tertiary Care Centre: An Observational Study.

作者信息

Jena Pramila, Tiwari Malvika, Panda Soumya R, Samantroy Subhra, Panda Jyochnamayi

机构信息

Obstetrics and Gynecology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.

Obstetrics and Gynecology, Ramakrishna Mission Seva Pratishthan, Kolkata, IND.

出版信息

Cureus. 2021 Dec 25;13(12):e20695. doi: 10.7759/cureus.20695. eCollection 2021 Dec.

Abstract

BACKGROUND

Polycystic ovary syndrome (PCOS) is a common disorder affecting mostly reproductive age group women. It is characterized by clinical and biochemical evidence of anovulation, hyperandrogenism and a polycystic ovary in the ultrasound. The aim of the present study is to find out the prevalence of cutaneous manifestations in PCOS and the correlation of their cutaneous manifestations with body mass index (BMI).

MATERIALS AND METHODS

A hospital-based observational, prospective study was conducted with 251 patients over a period of 18 months. Patients were divided into two groups based on their BMI values (more than 25 and less than 25) and screened for cutaneous manifestations. Correlation between the cutaneous manifestations and BMI was noted.

RESULTS

Maximum number of manifestations were seen in overweight patients (n=189). Hirsutism was the most common cutaneous manifestation followed by acne. But the only statistically significant association noted in the present study was between acne and BMI (p-value 0.009).

CONCLUSION

PCOS is a common disorder seen in females of the reproductive age group. Though the prevalence of cutaneous manifestations was more commonly seen in overweight (BMI between 25 and 30) and obese women (BMI >30), they were also found in lean groups. Hence evaluation and counselling regarding lifestyle modification are important not only for obese but also in lean PCOS.

摘要

背景

多囊卵巢综合征(PCOS)是一种常见疾病,主要影响育龄期女性。其特征为无排卵、高雄激素血症的临床和生化证据,以及超声检查显示的多囊卵巢。本研究的目的是找出PCOS患者皮肤表现的患病率及其皮肤表现与体重指数(BMI)的相关性。

材料与方法

在18个月的时间里,对251例患者进行了一项基于医院的观察性前瞻性研究。根据患者的BMI值(大于25和小于25)将患者分为两组,并对皮肤表现进行筛查。记录皮肤表现与BMI之间的相关性。

结果

超重患者(n = 189)出现的表现最多。多毛症是最常见的皮肤表现,其次是痤疮。但本研究中唯一具有统计学意义的关联是痤疮与BMI之间的关联(p值0.009)。

结论

PCOS是育龄期女性中常见的疾病。虽然皮肤表现的患病率在超重(BMI在25至30之间)和肥胖女性(BMI>30)中更为常见,但在瘦人群体中也有发现。因此,不仅对肥胖的PCOS患者,而且对瘦的PCOS患者,进行生活方式改变的评估和咨询都很重要。

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本文引用的文献

1
The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review.多囊卵巢综合征的患病率:一项简要的系统评价。
J Hum Reprod Sci. 2020 Oct-Dec;13(4):261-271. doi: 10.4103/jhrs.JHRS_95_18. Epub 2020 Dec 28.

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