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人工尿道括约肌植入术后常见下尿路症状。

Lower Urinary Tract Symptoms are Common After Artificial Urinary Sphincter Implantation.

机构信息

Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Severance Hospital, Seoul, Republic of Korea.

Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Severance Hospital, Seoul, Republic of Korea.

出版信息

Urology. 2022 Jul;165:343-350. doi: 10.1016/j.urology.2022.01.031. Epub 2022 Jan 31.

Abstract

OBJECTIVE

To investigate lower urinary tract symptoms (LUTS) observed after artificial urinary sphincter (AUS) implantation for post-radical prostatectomy urinary incontinence (PRPUI).

MATERIALS AND METHODS

Cases of AUS for PRPUI were evaluated. Stress urinary incontinence (SUI) was assessed using the Sandvik-incontinence severity index. Other LUTS were evaluated using the overactive bladder symptom score and international prostate symptom score. The prevalence and predictive risk factors for post-AUS LUTS were analyzed.

RESULTS

Of 129 patients evaluated (mean follow-up = 42.3 months, mean age = 76.7 years), 8.5% had very severe SUI, 78.4% had moderately to severely symptomatic LUTS (IPSS = 8-35 points), and 45.2% were dissatisfied with their urinary condition. Nocturia was the most prevalent (48.0%). Maximum cystometric capacity (rho = -0.236, P = .007) and involuntary detrusor contraction (P = .002) were significantly related to the severity of post-AUS urgency urinary incontinence (UUI). Multivariable linear regression analysis indicated that involuntary detrusor contraction was more associated with post-AUS urgency (P <.001) and UUI (P = .006) than any other preoperative parameter. Age significantly correlated with the severity of post-AUS urgency (rho = 0.309, P <.001), UUI (rho = 0.196, P = .026), and the need for straining to void (rho = 0.240, P = .007).

CONCLUSION

Even after successful placement of an AUS, many patients were dissatisfied with various LUTS, ranging from the most frequent nocturia to the need for straining to void. Attention should be paid not only to SUI but also to non-SUI LUTS, which are observed in the general population in this age group and change over time. Counseling to educate patients about expected outcomes and continuous monitoring and treatment for LUTS should be provided for the PRPUI-AUS population.

摘要

目的

研究前列腺根治术后尿失禁(PRPUI)患者行人工尿道括约肌(AUS)植入术后出现的下尿路症状(LUTS)。

材料与方法

评估 PRPUI 患者的 AUS 病例。使用 Sandvik 尿失禁严重程度指数评估压力性尿失禁(SUI)。使用膀胱过度活动症症状评分和国际前列腺症状评分评估其他 LUTS。分析 AUS 后 LUTS 的发生率和预测风险因素。

结果

在 129 例患者中(平均随访时间为 42.3 个月,平均年龄为 76.7 岁),8.5%患者有非常严重的 SUI,78.4%患者有中至重度症状性 LUTS(IPSS 为 8-35 分),45.2%患者对其尿控状况不满意。夜尿最常见(48.0%)。最大膀胱容量(rho=-0.236,P=0.007)和不自主逼尿肌收缩(P=0.002)与 AUS 后急迫性尿失禁(UUI)的严重程度显著相关。多变量线性回归分析表明,不自主逼尿肌收缩与 AUS 后急迫性(P<0.001)和 UUI(P=0.006)的相关性强于任何其他术前参数。年龄与 AUS 后急迫性(rho=0.309,P<0.001)、UUI(rho=0.196,P=0.026)和需要用力排尿(rho=0.240,P=0.007)的严重程度显著相关。

结论

即使成功植入 AUS,许多患者仍对各种 LUTS 感到不满,范围从最常见的夜尿到需要用力排尿。不仅要关注 SUI,还要关注非 SUI LUTS,因为这些症状在该年龄段的普通人群中很常见,而且会随时间变化。应向 PRPUI-AUS 患者提供有关预期结果的咨询,并对 LUTS 进行持续监测和治疗。

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