Skirzewski Miguel, Molotchnikoff Stéphane, Hernandez Luis F, Maya-Vetencourt José Fernando
Rodent Cognition Research and Innovation Core, University of Western Ontario, London, ON, Canada.
Département de Sciences Biologiques, Université de Montréal, Montreal, QC, Canada.
Front Mol Neurosci. 2022 Jan 17;14:806376. doi: 10.3389/fnmol.2021.806376. eCollection 2021.
In the mammalian brain, information processing in sensory modalities and global mechanisms of multisensory integration facilitate perception. Emerging experimental evidence suggests that the contribution of multisensory integration to sensory perception is far more complex than previously expected. Here we revise how associative areas such as the prefrontal cortex, which receive and integrate inputs from diverse sensory modalities, can affect information processing in unisensory systems processes of down-stream signaling. We focus our attention on the influence of the medial prefrontal cortex on the processing of information in the visual system and whether this phenomenon can be clinically used to treat higher-order visual dysfunctions. We propose that non-invasive and multisensory stimulation strategies such as environmental enrichment and/or attention-related tasks could be of clinical relevance to fight cerebral visual impairment.
在哺乳动物大脑中，感觉模态的信息处理以及多感觉整合的全局机制有助于感知。新出现的实验证据表明，多感觉整合对感觉感知的贡献远比之前预期的要复杂得多。在这里，我们修正了诸如前额叶皮层等联合区域如何接收和整合来自不同感觉模态的输入，进而影响单感觉系统中信息处理（下游信号传导过程）的方式。我们将注意力集中在内侧前额叶皮层对视觉系统信息处理的影响，以及这种现象是否可在临床上用于治疗高阶视觉功能障碍。我们提出，诸如环境丰富化和/或注意力相关任务等非侵入性多感觉刺激策略可能在对抗大脑性视觉损伤方面具有临床相关性。
