Institute of Allied Health Sciences, De Montfort University, Leicester, UK.
Centre for Postgraduate Medicine and Public Health, University of Hertfordshire, Hatfield, Hertfordshire, UK.
Clin Exp Dermatol. 2022 Jun;47(6):1109-1114. doi: 10.1111/ced.15122. Epub 2022 Mar 4.
Hyperhidrosis is a common skin condition characterized by excessive sweating, which can negatively impact on quality of life. It is under-researched compared with other conditions of similar prevalence.
To generate a Top 10 list of research priorities for the treatment and management of hyperhidrosis, with equal input from people with hyperhidrosis and healthcare professionals (HCPs).
A priority setting partnership (PSP) was established and processes from the James Lind Alliance Handbook were followed. An online survey asked participants what questions they would like research to answer. These questions were grouped into 'indicative questions', which were ranked in a second survey of 45 indicative questions. The top 23 questions were then taken to a final workshop event attended by key stakeholders, and ranked to generate the Top 10 list of research priorities.
There were 592 questions submitted by 268 respondents for the first survey. For the second survey, 286 participants ranked the indicative questions in order of priority. At the final workshop, the Top 10 list was generated. The top three priorities were: (i) Are there any safe and effective permanent solutions for hyperhidrosis? (ii) What is the most effective and safe oral treatment (drugs taken by mouth) for hyperhidrosis? and (iii) What are the most effective and safe ways to reduce sweating in particular areas of the body?
There are many unanswered research questions that both people with hyperhidrosis and HCPs would like to see answered. The results from this PSP will help to ensure future research funding can be directed to these areas of priority.
多汗症是一种常见的皮肤疾病，其特征是过度出汗，这会对生活质量产生负面影响。与其他同等发病率的疾病相比，多汗症的研究相对较少。
旨在与多汗症患者和医疗保健专业人员（HCP）平等参与的情况下，生成治疗和管理多汗症的十大研究重点。
建立了一个优先级设定伙伴关系（PSP），并遵循了詹姆斯林德联盟手册中的流程。一项在线调查要求参与者提出他们希望研究回答的问题。这些问题被分为“指示性问题”，在对 45 个指示性问题的第二项调查中对这些问题进行排名。然后，将前 23 个问题提交给一个由主要利益相关者参加的最终研讨会活动，并对其进行排名，以生成十大研究重点清单。
第一次调查收到了 268 名受访者提交的 592 个问题。在第二次调查中，286 名参与者按照优先顺序对指示性问题进行了排名。在最终研讨会上，生成了十大研究重点清单。前三个重点是：（i）是否有任何安全有效的永久性多汗症解决方案？（ii）治疗多汗症最有效和安全的口服药物（口服药物）是什么？（iii）减少身体特定部位出汗的最有效和安全方法是什么？
有许多未解答的研究问题，无论是多汗症患者还是 HCP 都希望看到答案。该 PSP 的结果将有助于确保未来的研究资金能够投向这些优先领域。
