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新冠疫情期间新近无家可归人群中的药物过量问题。

Drug Overdoses During the COVID-19 Pandemic Among Recently Homeless Individuals.

机构信息

Harvard Medical School, Boston, MA, USA.

MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.

出版信息

Addiction. 2022 Jun;117(6):1692-1701. doi: 10.1111/add.15823. Epub 2022 Feb 14.

Abstract

AIMS

To examine how weekly rates of emergency department (ED) visits for drug overdoses changed among individuals with a recent history of homelessness (IRHH) and their housed counterparts during the pre-pandemic, peak, and re-opening periods of the first wave of the COVID-19 pandemic, using corresponding weeks in 2019 as a historical control.

DESIGN

Population-based retrospective cohort study conducted between September 30, 2018 and September 26, 2020.

SETTING

Ontario, Canada.

PARTICIPANTS

A total of 38 617 IRHH, 15 022 369 housed individuals, and 186 858 low-income housed individuals matched on age, sex, rurality, and comorbidity burden.

MEASUREMENTS

ED visits for drug overdoses of accidental and undetermined intent.

FINDINGS

Average rates of ED visits for drug overdoses between January and September 2020 were higher among IRHH compared with housed individuals (rate ratio [RR], 148.0; 95% CI, 142.7-153.5) and matched housed individuals (RR, 22.3; 95% CI, 20.7-24.0). ED visits for drug overdoses decreased across all groups by ~20% during the peak period (March 17 to June 16, 2020) compared with corresponding weeks in 2019. During the re-opening period (June 17 to September 26, 2020), rates of ED visits for drug overdoses were significantly higher among IRHH (RR, 1.56; 95% CI, 1.44-1.69), matched housed individuals (RR, 1.25; 95% CI, 1.08-1.46), and housed individuals relative to equivalent weeks in 2019 (RR, 1.07; 95% CI, 1.02-1.11). The relative increase in drug overdose ED visits among IRHH was larger compared with both matched housed individuals (P = 0.01 for interaction between group and year) and housed individuals (P < 0.001) during this period.

CONCLUSIONS

Recently homeless individuals in Ontario, Canada experienced disproportionate increases in ED visits for drug overdoses during the re-opening period of the COVID-19 pandemic compared with housed people.

摘要

目的

利用 2019 年同期数据作为历史对照,研究在 COVID-19 大流行第一波的无家可归者(IRHH)近期史和有房者的急诊就诊率在流行前、高峰期和重新开放期间的每周变化情况。

设计

2018 年 9 月 30 日至 2020 年 9 月 26 日进行的基于人群的回顾性队列研究。

地点

加拿大安大略省。

参与者

共有 38617 名 IRHH、15022369 名有房者和 186858 名低收入有房者,按年龄、性别、农村地区和合并症负担进行匹配。

测量

因意外和不明原因药物过量而导致的急诊就诊率。

发现

2020 年 1 月至 9 月期间,IRHH 的药物过量急诊就诊率高于有房者(比率比[RR],148.0;95%置信区间,142.7-153.5)和匹配的有房者(RR,22.3;95%置信区间,20.7-24.0)。与 2019 年同期相比,所有人群在高峰期(2020 年 3 月 17 日至 6 月 16 日)的药物过量急诊就诊率下降了约 20%。在重新开放期间(2020 年 6 月 17 日至 9 月 26 日),IRHH 的药物过量急诊就诊率明显高于有房者(RR,1.56;95%置信区间,1.44-1.69)、匹配的有房者(RR,1.25;95%置信区间,1.08-1.46)和有房者与 2019 年同期相比(RR,1.07;95%置信区间,1.02-1.11)。在此期间,IRHH 的药物过量急诊就诊率相对增加幅度大于匹配的有房者(P=0.01 用于组间和年份的交互作用)和有房者(P<0.001)。

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Estimating the uncertain effect of the COVID pandemic on drug overdoses.估算新冠大流行对药物过量的不确定影响。
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