动物收容所中入院猫携带产超广谱β-内酰胺酶肠杆菌科的粪便排出情况。
Fecal shedding of extended-spectrum beta-lactamase-producing Enterobacterales in cats admitted to an animal shelter.
机构信息
Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
出版信息
J Feline Med Surg. 2022 Dec;24(12):1301-1304. doi: 10.1177/1098612X221075602. Epub 2022 Feb 8.
OBJECTIVES
The objective of this study was to evaluate shedding of extended-spectrum beta-lactamase (ESBL)-producing bacteria in cats admitted to an animal shelter.
METHODS
Fecal samples were collected from cats admitted to an animal shelter between 12 June and 23 August 2018. Selective enrichment culture for ESBL-producing bacteria was performed and isolates were speciated and tested for selected ESBL genes using PCR.
RESULTS
ESBL-producing Enterobacterales were identified in fecal samples from 2/87 (2.3%; 95% confidence interval 0.6-8.0) cats. One isolate was an that possessed , and genes. The other was possessing and .
CONCLUSIONS AND RELEVANCE
While the study sample size and prevalence rate for ESBL-producing bacteria were low, these data document that cats admitted to similar shelters could harbor these agents. The risk posed by ESBL-producing bacterium shedding in cats, both to cats and other species, is currently unclear. However, these findings support the need for more investigation of interspecies transmission of ESBL-producing bacteria and ESBL genes, as well as the importance of antimicrobial stewardship and routine infection control measures.
目的
本研究旨在评估收容所中收容的猫科动物中产超广谱β-内酰胺酶（ESBL）细菌的脱落情况。
方法
2018 年 6 月 12 日至 8 月 23 日，从收容所收容的猫中采集粪便样本。对 ESBL 产生菌进行选择性增菌培养，并用 PCR 对分离株进行种属鉴定和特定 ESBL 基因检测。
结果
从 87 只猫（2.3%；95%置信区间 0.6-8.0）的粪便样本中鉴定出产 ESBL 的肠杆菌科细菌。其中一个分离株是 ，它携带 、 和 基因。另一个是 ，携带 和 基因。
结论和相关性
虽然研究样本量和产 ESBL 细菌的流行率较低，但这些数据表明，类似收容所收容的猫可能携带这些病原体。目前尚不清楚产 ESBL 细菌在猫体内脱落对猫和其他物种构成的风险。然而，这些发现支持需要进一步调查 ESBL 产生菌和 ESBL 基因的种间传播，以及抗菌药物管理和常规感染控制措施的重要性。
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