麸质对乳糜泻患者小肠上皮中HLA - DR的影响。
The effect of gluten on HLA-DR in the small intestinal epithelium of patients with coeliac disease.
作者信息
Ciclitira P J, Nelufer J M, Ellis H J, Evans D J
出版信息
Clin Exp Immunol. 1986 Jan;63(1):101-4.
Abstract
Frozen sections of control and coeliac jejunal mucosa were examined for HLA-DR staining. In general the staining pattern in the controls and treated coeliac patients was a patchy subapical pattern on villous tips. Untreated coeliac patients gave a different pattern with staining extending to the crypt enterocytes. Gluten challenge in three treated coeliac patients induced an altered staining pattern within 2 h.
摘要
对对照和乳糜泻空肠黏膜的冰冻切片进行HLA - DR染色检查。总体而言，对照组和接受治疗的乳糜泻患者的染色模式为绒毛尖端的斑片状顶端下模式。未经治疗的乳糜泻患者呈现出不同的模式，染色延伸至隐窝肠上皮细胞。三名接受治疗的乳糜泻患者在麸质激发后2小时内染色模式发生改变。
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