Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science & Technology, Huazhong Agricultural University, Wuhan, China.
CAS Key Laboratory of Insect Developmental and Evolutionary Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
PLoS One. 2022 Feb 10;17(2):e0263462. doi: 10.1371/journal.pone.0263462. eCollection 2022.
Detoxification enzymes play significant roles in the interactions between insects and host plants, wherein detoxification-related genes make great contributions. As herbivorous pests, aphids reproduce rapidly due to parthenogenesis. They are good biological materials for studying the mechanisms that allow insect adaptation to host plants. Insect detoxification gene families are associated with insect adaptation to host plants. The Aphidinae is the largest subfamily in the Aphididae with at least 2483 species in 256 genera in 2 tribes: the Macrosiphini (with 3/4 of the species) and the Aphidini. Most aphid pests on crops and ornamental plants are Aphidinae. Members of the Aphidinae occur in nearly every region of the world. The body shape and colour vary significantly. To research the role that detoxification gene families played in the process of aphid adaptation to host evolution, we analyzed the phylogeny and evolution of these detoxification gene families in Aphidinae. In general, the P450/GST/CCE gene families contract, whereas the ABC/UGT families are conserved in Aphidinae species compared to these families in other herbivorous insects. Genus-specific expansions of P450 CYP4, and GST Delta have occurred in the genus Acyrthosiphon. In addition, the evolutionary rates of five detoxification gene families in the evolution process of Aphidinae are different. The comparison of five detoxification gene families among nine Aphidinae species and the estimated relative evolutionary rates provided herein support an understanding of the interaction between and the co-evolution of Aphidinae and plants.
解毒酶在昆虫与宿主植物的相互作用中起着重要作用，其中解毒相关基因做出了巨大贡献。作为植食性害虫，蚜虫由于孤雌生殖而快速繁殖。它们是研究昆虫适应宿主植物机制的良好生物材料。昆虫解毒基因家族与昆虫适应宿主植物有关。蚜科中的蚜亚科是最大的亚科，至少有 256 属 2483 种，分为 2 个族：巨蚜族（占物种的 3/4）和蚜族。大多数农作物和观赏植物上的蚜虫都是蚜亚科。蚜亚科成员几乎存在于世界的每一个地区。它们的体型和颜色差异很大。为了研究解毒基因家族在蚜虫适应宿主进化过程中的作用，我们分析了蚜亚科这些解毒基因家族的系统发育和进化。一般来说，与其他植食性昆虫相比，蚜亚科的 P450/GST/CCE 基因家族收缩，而 ABC/UGT 家族则是保守的。在 Acyrthosiphon 属中，P450 CYP4 和 GST Delta 的基因发生了属特异性扩张。此外，在蚜亚科的进化过程中，五个解毒基因家族的进化速率不同。对 9 种蚜亚科物种中五个解毒基因家族的比较以及本文中估计的相对进化速率，支持了对蚜亚科和植物之间相互作用和共同进化的理解。
