Department of Obstetrics & Gynecology, Chungnam National University Hospital, Deajeon, Republic of Korea.
Department of Obstetrics & Gynecology, Chungnam National University Sejong Hospital, Sejong, Republic of Korea.
BMC Pregnancy Childbirth. 2022 Feb 10;22(1):113. doi: 10.1186/s12884-022-04438-z.
In twin pregnancies, the cord prolapse of either fetus during the pre-viable period leads to fetal death but can also cause an intrauterine infection, leading to death or prematu-re birth of the remaining fetus. However, there are no validated protocols to prolong the gestational period or decrease the morbidity and mortality of the remaining fetus.
The present cases were PPROM and cord prolapse very early during the second trimester (around 17 weeks in the first case and 19 weeks in the second case). The first fetus was evacuated, and cervical cerclage was performed at 23 and 20 weeks in the two cases, respectively. After maintaining the pregnancy, the second baby was born around 27 and 39 weeks in the first and second cases, respectively. The delivery interval between the first and second fetuses was 46 days in the first case and 126 days in the second case.
If cord prolapse is identified at a pre-viable time in twin fetuses, evacuation and cerclage should be performed as soon as possible after the cord prolapse to reduce intrauterine infection and increase the survival chances of the remaining fetus.
在双胎妊娠中,即使在可行孕周之前发生任一胎儿的脐带脱垂,也会导致胎儿死亡,但也可能导致宫内感染,继而导致存活胎儿死亡或早产。然而,目前尚无延长孕周或降低存活胎儿发病率和死亡率的有效方案。
本病例均为极早早孕期胎膜早破伴脐带脱垂(第一例发生于孕 17 周左右,第二例发生于孕 19 周)。第一例胎儿娩出后,两例患者分别于 23 周和 20 周行宫颈环扎术。继续妊娠后,第一例和第二例分别于孕 27 周和 39 周分娩,两例间的分娩间隔分别为 46 天和 126 天。
如果在双胎胎儿中于不可行孕周之前发现脐带脱垂,应在脐带脱垂后尽快行胎儿清除术和宫颈环扎术,以减少宫内感染并增加存活胎儿的生存机会。