Zec R F, Weinberger D R
Psychiatr Clin North Am. 1986 Mar;9(1):49-61.
Studies relating CT abnormalities to impairments on neuropsychological tests in schizophrenic patients are critically reviewed. The overall conclusion is that there appears to be an association between CT abnormalities and neuropsychological deficits in at least some schizophrenic patient samples. It is proposed that there may be two classes of CT abnormalities in schizophrenia: "incidental" versus "essential" CT abnormalities and that neuropsychological impairment above the baseline levels found in most schizophrenic patients may be associated only with the former type. Only attempts to replicate these findings in different schizophrenic samples drawn from different settings can reveal whether this association between CT abnormalities and neuropsychological deficits is widely generalizable.
对有关精神分裂症患者CT异常与神经心理学测试损伤之间关系的研究进行了批判性综述。总体结论是，至少在一些精神分裂症患者样本中，CT异常与神经心理学缺陷之间似乎存在关联。有人提出，精神分裂症可能存在两类CT异常：“偶然的”与“本质的”CT异常，并且大多数精神分裂症患者基线水平之上的神经心理学损伤可能仅与前一种类型相关。只有尝试在来自不同环境的不同精神分裂症样本中重复这些发现，才能揭示CT异常与神经心理学缺陷之间的这种关联是否具有广泛的普遍性。
