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本文引用的文献

1
Current Insights Into the Pathophysiology of Multisystem Inflammatory Syndrome in Children.儿童多系统炎症综合征病理生理学的当前见解
Curr Pediatr Rep. 2021;9(4):83-92. doi: 10.1007/s40124-021-00257-6. Epub 2021 Oct 19.
2
Multi-inflammatory syndrome and Kawasaki disease in children during the COVID-19 pandemic: A nationwide register-based study and time series analysis.儿童 COVID-19 大流行期间的多系统炎症综合征和川崎病:一项基于全国登记的研究和时间序列分析。
Acta Paediatr. 2021 Nov;110(11):3063-3068. doi: 10.1111/apa.16051. Epub 2021 Aug 4.
3
Recent Experience: Corticosteroids as a First-line Therapy in Children With Multisystem Inflammatory Syndrome and COVID-19-related Myocardial Damage.近期经验:皮质类固醇作为 COVID-19 相关心肌损伤的儿童多系统炎症综合征的一线治疗药物。
Pediatr Infect Dis J. 2021 Nov 1;40(11):e390-e394. doi: 10.1097/INF.0000000000003260.
4
Treatment of Multisystem Inflammatory Syndrome in Children.儿童多系统炎症综合征的治疗。
N Engl J Med. 2021 Jul 1;385(1):11-22. doi: 10.1056/NEJMoa2102968. Epub 2021 Jun 16.
5
Multisystem inflammatory syndrome in children (MISC): A systematic review.儿童多系统炎症综合征(MISC):系统评价。
Int J Clin Pract. 2021 Nov;75(11):e14450. doi: 10.1111/ijcp.14450. Epub 2021 Jun 23.
6
Successful Treatment of Pediatric Inflammatory Multisystem Syndrome Temporally Associated with COVID-19 (PIMS-TS) with Split Doses of Immunoglobulin G and Estimation of PIMS-TS Incidence in a County District in Southern Germany.采用分剂量免疫球蛋白G成功治疗与新冠病毒病相关的儿童炎症性多系统综合征(PIMS-TS)并估算德国南部某县区PIMS-TS发病率
Healthcare (Basel). 2021 Apr 18;9(4):481. doi: 10.3390/healthcare9040481.
7
Strategic management of pediatric intensive care unit in a tertiary children's hospital in southwest China during the COVID-19 pandemic.中国西南部一家三级儿童医院在新冠疫情期间儿科重症监护病房的战略管理
Transl Pediatr. 2020 Dec;9(6):849-862. doi: 10.21037/tp-20-422.
8
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study.英国因 COVID-19 住院的儿童和青少年的临床特征:前瞻性多中心观察队列研究。
BMJ. 2020 Aug 27;370:m3249. doi: 10.1136/bmj.m3249.
9
The Wide Spectrum of COVID-19 Clinical Presentation in Children.儿童新冠病毒感染的广泛临床表现谱
J Clin Med. 2020 Sep 12;9(9):2950. doi: 10.3390/jcm9092950.
10
Can data from paediatric cohorts solve the COVID-19 puzzle?儿科队列数据能否解开 COVID-19 之谜?
PLoS Pathog. 2020 Sep 9;16(9):e1008798. doi: 10.1371/journal.ppat.1008798. eCollection 2020 Sep.

严重急性呼吸综合征冠状病毒2大流行对瑞士儿科重症监护病房的管理产生影响。

The SARS-CoV-2 Pandemic Impacts the Management of Swiss Pediatric Intensive Care Units.

作者信息

Soomann Maarja, Wendel-Garcia Pedro D, Kaufmann Mark, Grazioli Serge, Perez Marie-Helene, Hilty Matthias P, André Maya C, Brotschi Barbara

机构信息

Department of Pediatric and Neonatal Intensive Care, University Children's Hospital Zurich, Zurich, Switzerland.

Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.

出版信息

Front Pediatr. 2022 Jan 28;10:761815. doi: 10.3389/fped.2022.761815. eCollection 2022.

DOI:10.3389/fped.2022.761815
PMID:35155302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8832059/
Abstract

The impact of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic on pediatric intensive care units (PICUs) is difficult to quantify. We conducted an observational study in all eight Swiss PICUs between 02/24/2020 and 06/15/2020 to characterize the logistical and medical aspects of the pandemic and their impact on the management of the Swiss PICUs. The nine patients admitted to Swiss PICUs during the study period suffering from pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) and constituting 14% (9/63) of all SARS-CoV-2 positive hospitalized patients in Swiss children's hospitals caused a higher workload [total Nine Equivalents of nursing Manpower use Score (NEMS) points, = 0.0008] and were classified to higher workload categories ( < 0.0001) than regular PICU patients ( = 4,881) admitted in 2019. The comparison of the characteristics of the eight Swiss PICUs shows that they were confronted by different organizational issues arising from temporary regulations put in place by the federal council. These general regulations had different consequences for the eight individual PICUs due to the differences between the PICUs. In addition, the temporal relationship of these different regulations influenced the available PICU resources, dependent on the characteristics of the individual PICUs. As pandemic continues, reflecting and learning from experience is essential to reduce workload, optimize bed occupancy and manage resources in each individual PICU. In a small country as Switzerland, with a relatively decentralized health care local differences between PICUs are considerable and should be taken into account when making policy decisions.

摘要

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)大流行对儿科重症监护病房(PICU)的影响难以量化。我们于2020年2月24日至2020年6月15日期间在瑞士所有8个PICU进行了一项观察性研究,以描述大流行的后勤和医疗方面及其对瑞士PICU管理的影响。在研究期间,瑞士PICU收治的9例患有与SARS-CoV-2暂时相关的儿童炎症性多系统综合征(PIMS-TS)的患者,占瑞士儿童医院所有SARS-CoV-2阳性住院患者的14%(9/63),导致了更高的工作量[护理人力使用总等效评分(NEMS)总分, = 0.0008],并且与2019年收治的常规PICU患者( = 4,881)相比,被归类为更高的工作量类别( < 0.0001)。对瑞士8个PICU的特征进行比较表明,它们面临着由联邦委员会制定的临时规定引发的不同组织问题。由于各PICU之间存在差异,这些一般规定对8个独立的PICU产生了不同的影响。此外,这些不同规定的时间关系影响了可用的PICU资源,这取决于各个PICU的特征。随着大流行的持续,反思并从经验中学习对于减少工作量、优化床位占用率以及管理每个独立PICU的资源至关重要。在瑞士这样一个小国,医疗保健相对分散,PICU之间的局部差异相当大,在制定政策决策时应予以考虑。