银质沉着症：使用石蜡包埋组织的微观分析与形态学相关性研究

Argyria: microanalytic-morphologic correlation using paraffin-embedded tissue.

作者信息

Landas S, Bonsib S M, Ellerbroek R, Fischer J

出版信息

Ultrastruct Pathol. 1986;10(2):129-35. doi: 10.3109/01913128609014589.

DOI:10.3109/01913128609014589

Abstract

Scanning electron microscopes, which have energy dispersive spectroscopy (x-ray microanalysis) capability, can provide accurate identification of the composition of inorganic deposits in tissue. We report a case of florid argyria in which the same deparaffinized 4-micron sections were sequentially examined by light microscopy, scanning electron microscopy, backscattered electron imaging, and x-ray microanalysis to confirm the clinical impression of argyria. We recommend the use of x-ray microanalysis of paraffin-embedded tissue as a simple, rapid and inexpensive means of precise identification of inorganic deposits of heavy elements in tissue sections.

摘要

具有能量色散光谱（X射线微分析）功能的扫描电子显微镜能够准确鉴定组织中无机沉积物的成分。我们报告了一例重度银沉着病病例，对同一经脱蜡处理的4微米切片依次进行光学显微镜检查、扫描电子显微镜检查、背散射电子成像和X射线微分析，以证实银沉着病的临床诊断。我们建议将石蜡包埋组织的X射线微分析作为一种简单、快速且经济的方法，用于精确鉴定组织切片中重金属元素的无机沉积物。