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关于调节生物活性化合物从生物聚合物基质中释放速率方法的批判性综述。

A critical review on approaches to regulate the release rate of bioactive compounds from biopolymeric matrices.

作者信息

Sabaghi Moslem, Tavasoli Sedighe, Hoseyni Seyedeh Zahra, Mozafari M R, Degraeve Pascal, Katouzian Iman

机构信息

Univ Lyon, Université Lyon 1, ISARA Lyon, BioDyMIA Research Unit, Technopole Alimentec, 155 rue Henri de Boissieu, F-01000 Bourg en Bresse, France.

Department of Food Science and Technology, University of Agricultural Sciences and Natural Resources, Gorgan, Iran.

出版信息

Food Chem. 2022 Jul 15;382:132411. doi: 10.1016/j.foodchem.2022.132411. Epub 2022 Feb 9.

DOI:10.1016/j.foodchem.2022.132411
PMID:35158271
Abstract

Recently, there has been a growing interest in novel food formulations and packaging materials using controlled release systems in order to enhance the functional performance of food bioactive ingredients and to prolong the shelf-life of food products. Correspondingly, numerous types of matrices (polymers, biopolymers, synthetic materials) could be implemented as carriers based on their compatibility with the bioactive ingredients and the type of releasing medium. A plethora of applications of controlled release can be identified in the pharmaceutical, agriculture, cosmetics, and particularly the food industries. Moreover, several physical and chemical stimuli are applied to regulate the release behavior of a bioactive molecule in the desired medium, which is under development. This review highlights the strategies applied to regulate the release rate of biopolymeric networks mainly including mixing of biopolymers, physical and chemical crosslinkers along with encapsulation systems, furthermore, the future prospects of release concept are discussed.

摘要

最近,人们对使用控释系统的新型食品配方和包装材料越来越感兴趣,目的是提高食品生物活性成分的功能性能并延长食品的保质期。相应地,基于它们与生物活性成分的相容性和释放介质的类型,多种类型的基质(聚合物、生物聚合物、合成材料)可被用作载体。控释在制药、农业、化妆品尤其是食品工业中有大量应用。此外,正在开发几种物理和化学刺激来调节生物活性分子在所需介质中的释放行为。本综述重点介绍了用于调节生物聚合物网络释放速率的策略,主要包括生物聚合物、物理和化学交联剂的混合以及包封系统,此外,还讨论了释放概念的未来前景。

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