Athanasakopoulou Zoi, Sofia Marina, Giannakopoulos Alexios, Papageorgiou Konstantinos, Chatzopoulos Dimitris C, Spyrou Vassiliki, Petridou Evanthia, Petinaki Efthymia, Billinis Charalambos
Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.
Faculty of Public and One Health, University of Thessaly, 43100 Karditsa, Greece.
Animals (Basel). 2022 Jan 30;12(3):340. doi: 10.3390/ani12030340.
is an Enterobacteriaceae with unclarified dispersion and pathogenicity. During an ongoing investigation about antimicrobial resistance in Greece, the occurrence of was evaluated among wild birds and humans. A total of 445 wild bird and 2000 human fecal samples were collected and screened for the presence of the organism. Subsequently, all strains were phenotypically and molecularly characterized regarding their antimicrobial resistance characteristics. Four were isolated from a common pheasant (), two Eurasian magpies () and a great white-fronted goose (). Among these four strains, the three latter presented resistance to 3rd generation cephalosporins, were phenotypically confirmed to produce ESBLs and were found to harbor . The three ESBL isolates additionally exhibited resistance to tetracyclines, while resistance to aminoglycosides was detected in two of them and to trimethoprim/sulfamethoxazole in one. No strains were retrieved from the human samples tested. This is the first report that provides evidence of dissemination among wild birds in Greece, describing CTX-M-1 production in multidrug resistant wild birds' isolates of this bacterial species.
是一种传播情况和致病性尚不明确的肠杆菌科细菌。在希腊正在进行的一项关于抗菌药物耐药性的调查中，对野生鸟类和人类中该细菌的出现情况进行了评估。总共收集了445份野生鸟类粪便样本和2000份人类粪便样本，并对样本中该生物体的存在情况进行了筛查。随后，对所有分离菌株的抗菌药物耐药特性进行了表型和分子特征分析。从一只环颈雉（）、两只喜鹊（）和一只白额雁（）中分离出了四株该细菌。在这四株菌株中，后三株对第三代头孢菌素耐药，经表型确认产生超广谱β-内酰胺酶（ESBLs），并发现携带。这三株产ESBLs的菌株还对四环素耐药，其中两株对氨基糖苷类耐药，一株对甲氧苄啶/磺胺甲恶唑耐药。在所检测的人类样本中未检出该细菌菌株。这是第一份提供证据证明该细菌在希腊野生鸟类中传播的报告，描述了该细菌多重耐药野生鸟类分离株中CTX-M-1的产生情况。
