Niculescu Adelina-Gabriela, Grumezescu Alexandru Mihai
Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, 011061 Bucharest, Romania.
Research Institute of the University of Bucharest-ICUB, University of Bucharest, 050657 Bucharest, Romania.
Polymers (Basel). 2022 Jan 21;14(3):421. doi: 10.3390/polym14030421.
Whether they are caused by trauma, illness, or surgery, wounds may occur throughout anyone's life. Some injuries' complexity and healing difficulty pose important challenges in the medical field, demanding novel approaches in wound management. A highly researched possibility is applying biomaterials in various forms, ranging from thin protective films, foams, and hydrogels to scaffolds and textiles enriched with drugs and nanoparticles. The synergy of biocompatibility and cell proliferative effects of these materials is reflected in a more rapid wound healing rate and improved structural and functional properties of the newly grown tissue. This paper aims to present the biomaterial dressings and scaffolds suitable for wound management application, reviewing the most recent studies in the field.
无论伤口是由创伤、疾病还是手术引起的,任何人一生中都可能出现。一些损伤的复杂性和愈合难度给医学领域带来了重大挑战,需要在伤口处理方面采用新方法。一种经过大量研究的可能性是应用各种形式的生物材料,从薄的保护膜、泡沫、水凝胶到富含药物和纳米颗粒的支架及纺织品。这些材料的生物相容性和细胞增殖效应的协同作用体现在伤口愈合速度加快以及新生长组织的结构和功能特性得到改善。本文旨在介绍适用于伤口处理应用的生物材料敷料和支架,回顾该领域的最新研究。