基于光声光谱的人体无创健康监测

College of Automation, Hangzhou Dianzi University, Hangzhou 310018, Zhejiang, China.

Zhejiang Lab, Hangzhou 311121, Zhejiang, China.

Sensors (Basel). 2022 Feb 3;22(3):1155. doi: 10.3390/s22031155.

For certain diseases, the continuous long-term monitoring of the physiological condition is crucial. Therefore, non-invasive monitoring methods have attracted widespread attention in health care. This review aims to discuss the non-invasive monitoring technologies for human health based on photoacoustic spectroscopy. First, the theoretical basis of photoacoustic spectroscopy and related devices are reported. Furthermore, this article introduces the monitoring methods for blood glucose, blood oxygen, lipid, and tumors, including differential continuous-wave photoacoustic spectroscopy, microscopic photoacoustic spectroscopy, mid-infrared photoacoustic detection, wavelength-modulated differential photoacoustic spectroscopy, and others. Finally, we present the limitations and prospects of photoacoustic spectroscopy.

对于某些疾病来说，持续的长期生理状态监测至关重要。因此，非侵入式监测方法在医疗保健领域引起了广泛关注。本综述旨在讨论基于光声光谱学的人体健康非侵入式监测技术。首先，报告了光声光谱学的理论基础和相关设备。此外，本文还介绍了血糖、血氧、血脂和肿瘤的监测方法，包括差频连续波光声光谱学、微观光声光谱学、中红外光声探测、波长调制差频光声光谱学等。最后，提出了光声光谱学的局限性和展望。