干细胞移植和细胞游离治疗牙周再生。
Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration.
机构信息
Institute of Dental Research, Osaka Dental University, Osaka 573-1121, Japan.
Department of Periodontology, Osaka Dental University, Osaka 573-1121, Japan.
出版信息
Int J Mol Sci. 2022 Jan 18;23(3):1011. doi: 10.3390/ijms23031011.
Abstract
Increasing attention has been paid to cell-based medicines. Many in vivo and in vitro studies have demonstrated the efficacy of stem cell transplantation for the regeneration of periodontal tissues over the past 20 years. Although positive evidence has accumulated regarding periodontal regeneration using stem cells, the exact mechanism of tissue regeneration is still largely unknown. This review outlines the practicality and emerging problems of stem cell transplantation therapy for periodontal regeneration. In addition, possible solutions to these problems and cell-free treatment are discussed.
摘要
人们越来越关注基于细胞的药物。在过去的 20 年中，许多体内和体外研究已经证明了干细胞移植对于牙周组织再生的有效性。尽管已经积累了关于使用干细胞进行牙周再生的积极证据，但组织再生的确切机制在很大程度上仍然未知。本文概述了干细胞移植治疗牙周再生的实用性和新出现的问题。此外，还讨论了这些问题的可能解决方案和无细胞治疗。
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