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慢性变应性鼻-鼻窦炎的每日生理盐水鼻腔冲洗:一份自述病例报告

Daily Saline Nasal Douching for Chronic Allergic Rhinosinusitis: An Autobiographical Case Report.

作者信息

Lakkireddy Maheshwar

机构信息

Department of Orthopaedics, All India Institute of Medical Sciences, Bibinagar, Hyderabad, IND.

出版信息

Cureus. 2022 Jan 12;14(1):e21153. doi: 10.7759/cureus.21153. eCollection 2022 Jan.

Abstract

Chronic allergic rhinosinusitis is a debilitating condition in a group of susceptible individuals with multifactorial etiology. I present my case of suffering from chronic allergic rhinosinusitis for 25 years treated with multiple drugs and surgeries with no relief. Adjunctive daily saline nasal douching has provided significant relief for three years to date. Genetic susceptibility with defective ciliary clearance, mucosal metaplasia with increased goblet cells secreting thick and inspissated mucus blocking the normal drainage, and stasis of secretions with inadequate mucosal immunity predisposes to polymicrobial infections, including fungal infections, antimicrobial resistance, and recurrent episodes of rhinosinusitis. Medical and surgical strategies often fail to manage this condition appropriately in a few cases. Adjunctive daily saline nasal douching is a safe and effective alternative to manage the debilitating symptoms of chronic allergic rhinosinusitis.

摘要

慢性变应性鼻-鼻窦炎是一组易感个体中病因多因素的使人衰弱的疾病。我讲述了自己患慢性变应性鼻-鼻窦炎25年的病例,期间接受了多种药物治疗和手术,但均无缓解。迄今为止,辅助性每日盐水鼻腔冲洗已显著缓解症状三年。纤毛清除功能缺陷的遗传易感性、杯状细胞增多导致黏膜化生并分泌浓稠黏液阻塞正常引流、分泌物淤滞以及黏膜免疫不足易引发包括真菌感染在内的多种微生物感染、抗菌药物耐药性和鼻-鼻窦炎反复发作。在少数情况下,药物和手术治疗策略往往无法有效控制这种疾病。辅助性每日盐水鼻腔冲洗是一种安全有效的替代方法,可用于缓解慢性变应性鼻-鼻窦炎使人衰弱的症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dec8/8833096/4bbf161e7206/cureus-0014-00000021153-i01.jpg

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