Suppr超能文献

任务诱发的面部情绪范式中的神经激活的可靠性:扫描仪和心理过程的影响。

Reliability of task-evoked neural activation during face-emotion paradigms: Effects of scanner and psychological processes.

机构信息

Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.

Scientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.

出版信息

Hum Brain Mapp. 2022 May;43(7):2109-2120. doi: 10.1002/hbm.25723. Epub 2022 Feb 15.

Abstract

Assessing and improving test-retest reliability is critical to efforts to address concerns about replicability of task-based functional magnetic resonance imaging. The current study uses two statistical approaches to examine how scanner and task-related factors influence reliability of neural response to face-emotion viewing. Forty healthy adult participants completed two face-emotion paradigms at up to three scanning sessions across two scanners of the same build over approximately 2 months. We examined reliability across the main task contrasts using Bayesian linear mixed-effects models performed voxel-wise across the brain. We also used a novel Bayesian hierarchical model across a predefined whole-brain parcellation scheme and subcortical anatomical regions. Scanner differences accounted for minimal variance in temporal signal-to-noise ratio and task contrast maps. Regions activated during task at the group level showed higher reliability relative to regions not activated significantly at the group level. Greater reliability was found for contrasts involving conditions with clearly distinct visual stimuli and associated cognitive demands (e.g., face vs. nonface discrimination) compared to conditions with more similar demands (e.g., angry vs. happy face discrimination). Voxel-wise reliability estimates tended to be higher than those based on predefined anatomical regions. This work informs attempts to improve reliability in the context of task activation patterns and specific task contrasts. Our study provides a new method to estimate reliability across a large number of regions of interest and can inform researchers' selection of task conditions and analytic contrasts.

摘要

评估和提高测试-重测可靠性对于解决基于任务的功能磁共振成像可重复性问题至关重要。本研究使用两种统计方法来研究扫描仪和与任务相关的因素如何影响对人脸情绪观看的神经反应的可靠性。40 名健康成年参与者在大约 2 个月内,在两台相同型号的扫描仪上完成了两个面部表情范式,最多可进行三次扫描。我们使用基于体素的全脑分割方案和皮质下解剖区域的新贝叶斯层次模型,在整个大脑范围内进行了基于贝叶斯线性混合效应模型的主要任务对比的可靠性研究。扫描仪差异仅解释了时间信号与噪声比和任务对比图的微小变化。在组水平上激活的区域相对于组水平上未显著激活的区域具有更高的可靠性。与具有更相似要求的条件(例如,愤怒面孔与快乐面孔的区分)相比,具有明显不同视觉刺激和相关认知要求的条件(例如,面孔与非面孔的区分)的对比具有更高的可靠性。基于体素的可靠性估计值往往高于基于预定义解剖区域的估计值。这项工作为在任务激活模式和特定任务对比的背景下提高可靠性提供了信息。我们的研究提供了一种新的方法,可以在大量感兴趣的区域中估计可靠性,并可以为研究人员选择任务条件和分析对比提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36a7/8996353/e6fc4df0c8b0/HBM-43-2109-g003.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验