State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.
State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.
Food Chem. 2022 Jul 30;383:132382. doi: 10.1016/j.foodchem.2022.132382. Epub 2022 Feb 10.
A molecularly imprinted electrochemical sensor (MIES) modified with Cu-MOF and TiCTx was successfully prepared for the detection of hygromycin B in food. According to the pH sensitive property of reversible borate ester bonds, a molecularly imprinted polymers (MIP) were constructed on the modified gold electrode (GE) surface by electropolymerization to realize the controllable elution and adsorption of template molecules. Cu-MOF with large specific surface area and TiCTx with excellent electrical conductivity cooperate to improve the overall analytical performance of MIES. The morphology and electrochemical performance of the sensor were evaluated. Under the optimal experimental conditions, the method showed superior selectivity to hygromycin B with a linear range of 5 × 10-5 × 10 M and a detection limit of 1.92 × 10 M (S/N = 3). The detection results of this method are in good agreement with HPLC-MS/MS, which proves that the method has reliable practicability and accuracy.
一种基于 Cu-MOF 和 TiCTx 修饰的分子印迹电化学传感器 (MIES) 被成功制备用于检测食品中的潮霉素 B。根据可逆硼酸酯键的 pH 敏感性，通过电聚合在修饰的金电极 (GE) 表面构建了分子印迹聚合物 (MIP)，以实现模板分子的可控洗脱和吸附。具有大比表面积的 Cu-MOF 和具有优异导电性的 TiCTx 协同作用，提高了 MIES 的整体分析性能。对传感器的形貌和电化学性能进行了评估。在最佳实验条件下，该方法对潮霉素 B 表现出优异的选择性，线性范围为 5×10-5×10 M，检测限为 1.92×10 M(S/N=3)。该方法的检测结果与 HPLC-MS/MS 吻合良好，证明该方法具有可靠的实用性和准确性。
