Firat Ilknur Tuncer, Polat Nihat, Firat Murat
Department of Ophthalmology, Inonu University School of Medicine, Malatya, Turkey.
Department of Ophthalmology, Malatya Training and Research Hospital, Malatya, Turkey.
Arq Bras Oftalmol. 2022 Feb 14;85(6):606-613. doi: 10.5935/0004-2749.20220088. eCollection 2022.
The aim of this study was to evaluate the effect of serous macular detachment observed during retinal vein occlusion on treatment results.
A total of 117 eyes from 115 patients who had been treated with intravitreal injections for macular edema secondary to retinal vein occlusion were retrospectively reviewed. Visual acuity, optical coherence tomography, and fundus fluorescein angiography findings were evaluated according to the status of serous macular detachment.
In the branch retinal vein occlusion group, a statistically significant increase was detected in the mean visual acuity compared to the baseline value at each visit in the absence of serous macular detachment, whereas the increase in the mean visual acuity was significant only at the 3- and 6-month visits in the presence of serous macular detachment. In the central retinal vein occlusion group, there was an increase in the mean visual acuity compared to the baseline value at every visit in the absence of serous macular detachment, whereas the mean visual acuity decreased compared to the baseline value at every visit except at the 3-month visit in the presence of serous macular detachment. The ellipsoid zone defect was more prominent in the presence of serous macular detachment in eyes with branch retinal vein occlusion, whereas there was no significant difference in the ellipsoid zone in the absence or presence of serous macular detachment in eyes with central retinal vein occlusion.
In the group with macular edema due to retinal vein occlusion, the initial mean visual acuity increase observed in the first year was maintained in cases without serous macular detachment but not in those with serous macular detachment. Serous macular detachment could be a negative factor in eyes with retinal vein occlusion.
本研究旨在评估视网膜静脉阻塞期间观察到的浆液性黄斑脱离对治疗效果的影响。
回顾性分析了115例接受玻璃体腔内注射治疗视网膜静脉阻塞继发黄斑水肿患者的117只眼。根据浆液性黄斑脱离的情况评估视力、光学相干断层扫描和眼底荧光血管造影结果。
在视网膜分支静脉阻塞组中，在没有浆液性黄斑脱离的情况下，每次随访时平均视力与基线值相比均有统计学意义的增加，而在有浆液性黄斑脱离的情况下，平均视力仅在3个月和6个月随访时显著增加。在视网膜中央静脉阻塞组中，在没有浆液性黄斑脱离的情况下，每次随访时平均视力与基线值相比均有增加，而在有浆液性黄斑脱离的情况下，除3个月随访外，每次随访时平均视力与基线值相比均下降。在视网膜分支静脉阻塞的眼中，浆液性黄斑脱离时椭圆体带缺损更明显，而在视网膜中央静脉阻塞的眼中，有无浆液性黄斑脱离时椭圆体带无显著差异。
在视网膜静脉阻塞所致黄斑水肿组中，无浆液性黄斑脱离的病例在第一年观察到的初始平均视力增加得以维持，而有浆液性黄斑脱离的病例则不然。浆液性黄斑脱离可能是视网膜静脉阻塞患者的一个不利因素。
