Ballerini Andrea, Tortorelli Marta, Marino Paolo, Appignanesi Cristina, Baschirotto Cinzia, Mallardo Luca, Tofani Tommaso, Pietrini Francesco, D'Anna Giulio, Rossi Andrea, Ricca Valdo, Santella Marina
Psychiatry Unit, Department of Health Science, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Department of Mental Health and Addictions, Central Tuscany NHS Trust, Florence, Italy.
Ann Gen Psychiatry. 2022 Feb 16;21(1):8. doi: 10.1186/s12991-022-00383-5.
Aberrant salience is the incorrect assignment of salience, significance, or value to different innocuous stimuli that might precede the onset of psychotic symptoms. The present study aimed to perform a preliminary evaluation of potentially different correlations between the Aberrant Salience Inventory (ASI) score and dimensional or categorical diagnostic approaches.
168 adult outpatients with a current psychiatric diagnosis were consecutively enrolled. Patients were evaluated using different psychometric scales. ASI was used to evaluate aberrant salience, and to evaluate the association between ASI scores and first rank symptoms (FRS), and/or with a psychiatric diagnosis. Principal dichotomic clusters of ASI were identified using the Chi-square automatic interaction detection (CHAID) method.
Current (16.76 ± 6.02 vs 13.37 ± 5.76; p = 0.001), lifetime (15.74 ± 6.08 vs 13.16 ± 5.74; p = 0.005) and past (15.75 ± 6.01 vs 13.33 ± 5.80; p = 0.009) FRS were the main clusters dichotomizing ASI. The average ASI score did not significantly differ among patients with different diagnoses.
ASI could be used as a tool to identify psychopathological dimensions, rather than the categorical diagnoses, in the schizophrenic spectrum.
异常显著性是指对可能先于精神病性症状发作的不同无害刺激错误地赋予显著性、重要性或价值。本研究旨在对异常显著性量表(ASI)得分与维度或分类诊断方法之间潜在的不同相关性进行初步评估。
连续纳入168名目前有精神科诊断的成年门诊患者。使用不同的心理测量量表对患者进行评估。ASI用于评估异常显著性,并评估ASI得分与一级症状(FRS)和/或精神科诊断之间的关联。使用卡方自动交互检测(CHAID)方法确定ASI的主要二分聚类。
当前(16.76±6.02对13.37±5.76;p = 0.001)、终生(15.74±6.08对13.16±5.74;p = 0.005)和过去(15.75±6.01对13.33±5.80;p = 0.009)的FRS是将ASI二分的主要聚类。不同诊断的患者之间平均ASI得分无显著差异。
在精神分裂症谱系中,ASI可作为识别精神病理维度而非分类诊断的工具。