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尼加拉瓜莱昂市基于城市人口队列的 SARS-CoV-2 感染血清流行病学。

Seroepidemiology of SARS-CoV-2 infections in an urban population-based cohort in León, Nicaragua.

机构信息

Center for Infectious Diseases Research, National Autonomous University of Nicaragua - León, León, Nicaragua.

Department of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

出版信息

Epidemiol Infect. 2021 Oct 20;149:e247. doi: 10.1017/S0950268821002144.

DOI:10.1017/S0950268821002144
PMID:35172912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8674192/
Abstract

In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselves, suggesting the importance of household transmission.

摘要

在尼加拉瓜基于人群的队列研究中，该国疫情的前 6 个月，SARS-CoV-2 血清阳性率达到 28%，6 个月后达到 35%。免疫衰减并不常见。家中有血清学阳性成员的个体自身呈血清学阳性的可能性是其三倍以上，这表明家庭传播的重要性。

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