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带有抗迁移单法兰的部分覆盖自膨式金属支架在超声内镜引导下肝胃造口术中发挥重要作用。

Partially covered self-expandable metal stent with antimigratory single flange plays important role during EUS-guided hepaticogastrostomy.

作者信息

Yamamura Masahiro, Ogura Takeshi, Ueno Saori, Okuda Atsushi, Nishioka Nobu, Yamada Masanori, Ueshima Kazuya, Matsuno Jun, Yamamoto Yoshitaro, Higuchi Kazuhide

机构信息

2nd Department of Internal Medicine, Osaka Medical College, Osaka, Japan.

出版信息

Endosc Int Open. 2022 Feb 15;10(2):E209-E214. doi: 10.1055/a-1729-0048. eCollection 2022 Feb.

Abstract

Stent migration into the abdominal cavity, which can occur due to stent shortening or stomach mobility, is a critical adverse event (AE) in EUS-HGS. To prevent this AE due to stent shortening, a novel, partially covered self-expandable metal stent with an antimigratory single flange has recently become available in Japan. The present study evaluated the clinical feasibility and safety of EUS-HGS using this novel stent.  We measured stent length in the abdominal cavity and the luminal portion after EUS-HGS using computed tomography (CT) performed 1 day after EUS-HGS (early phase). To evaluate stent shortening and the influence of stomach mobility, we also measured stent length at the same sites on CT performed at least 7 days after EUS-HGS (late phase).  Thirty-one patients successfully underwent EUS-HGS using this stent. According to CT in the early phase, stent length in the abdominal cavity was 7.13 ± 2.11 mm and the length of the luminal portion was 53.3 ± 6.27 mm. Conversely, according to CT in the late phase, stent length in the abdominal cavity was 8.55 ± 2.36 mm and the length of the luminal portion was 50.0 ± 8.36 mm. Stent shortening in the luminal portion was significantly greater in the late phase than in the early phase (  = 0.04).  CT showed that stent migration can occur even with successful stent deployment, due to various factors such as stent shortening. The antimigratory single flange may be helpful to prevent stent migration, but further prospective comparative studies are needed to confirm our results.

摘要

支架迁移至腹腔是超声内镜引导下胃空肠吻合术(EUS-HGS)中的一种严重不良事件(AE),其可能由于支架缩短或胃的活动度导致。为防止因支架缩短引起的这种不良事件,一种新型的、带有防迁移单法兰的部分覆盖自膨式金属支架最近在日本上市。本研究评估了使用这种新型支架进行EUS-HGS的临床可行性和安全性。我们在EUS-HGS后1天(早期)使用计算机断层扫描(CT)测量了EUS-HGS后腹腔内及管腔内部分的支架长度。为评估支架缩短情况及胃活动度的影响,我们还在EUS-HGS后至少7天(晚期)进行的CT上测量了相同部位的支架长度。31例患者成功使用该支架进行了EUS-HGS。根据早期CT,腹腔内支架长度为7.13±2.11mm,管腔内部分长度为53.3±6.27mm。相反,根据晚期CT,腹腔内支架长度为8.55±2.36mm,管腔内部分长度为50.0±8.36mm。管腔内部分的支架缩短在晚期显著大于早期(P = 0.04)。CT显示,即使支架成功置入,由于支架缩短等多种因素,仍可能发生支架迁移。防迁移单法兰可能有助于防止支架迁移,但需要进一步的前瞻性对照研究来证实我们的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a43b/8847065/274484ffea9d/10-1055-a-1729-0048-i2537ei1.jpg

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