Muskavitch M A, Kort E N, Springer M S, Goy M F, Adler J
Science. 1978 Jul 7;201(4350):63-5. doi: 10.1126/science.351803.
Normal Escherichia coli bacteria are repelled by acetate, benzoate, and indole and attracted by alpha-aminoisobutyrate. We have isolated mutants that are attracted to acetate, benzoate, and indole and may be repelled by alpha-aminoisobutyrate. These reversed-taxis mutants are defective in a central processing component: a set of methylated proteins known as MCP 1. The mechanism of reversal of taxis is discussed.
正常的大肠杆菌会被乙酸盐、苯甲酸盐和吲哚排斥,并被α-氨基异丁酸吸引。我们分离出了对乙酸盐、苯甲酸盐和吲哚有吸引力且可能被α-氨基异丁酸排斥的突变体。这些趋化性逆转突变体在一个核心处理组件中存在缺陷:一组被称为MCP 1的甲基化蛋白质。文中讨论了趋化性逆转的机制。