Department of Breast Surgery, First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
J Biomed Nanotechnol. 2022 Jan 1;18(1):50-60. doi: 10.1166/jbn.2022.3226.
Breast carcinoma remains one of the most common and fatal cancers, and even though a series of general therapeutic approaches have been used to treat breast cancer, their outcomes are significantly affected by a variety of side effects. However, nanomedicine could offer novel strategies for dealing with breast carcinoma. In fact, an increasing number of radionanomedicine approaches have recently been used in both diagnostics and therapy. To highlight this trend, the aim of the current review is to systemically summarize the latest advances in radionanomedicine, including single-modular imaging, multiple-modular imaging, and nanomedicine-based theranostics. Barriers to clinical application, the development of next-generation radionanomedicine, and challenges associated with future design are also discussed.
乳腺癌仍然是最常见和最致命的癌症之一,尽管已经采用了一系列一般的治疗方法来治疗乳腺癌,但其结果受到多种副作用的显著影响。然而,纳米医学可以为治疗乳腺癌提供新的策略。事实上,最近越来越多的放列纳米医学方法被用于诊断和治疗。为了突出这一趋势,本综述的目的是系统地总结放列纳米医学的最新进展,包括单模块成像、多模块成像和基于纳米医学的治疗。还讨论了临床应用的障碍、下一代放列纳米医学的发展以及与未来设计相关的挑战。