Nie J, Chen L, Yu C Q, Guo Y, Pei P, Chen J S, Chen Z M, Lyu J, Li Liming
Department of Epidemiology and Biostatistics, School of Public Health, Peking University/Peking University Center for Public Health and Epidemic Preparedness and Response/Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education,Beijing 100191, China.
Fuwai Hospital Chinese Academy of Medical Sciences, National Center for Cardiovascular Diseases, Beijing 100037, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2022 Feb 10;43(2):145-153. doi: 10.3760/cma.j.cn112338-20201201-01369.
To investigate the association between tea consumption and the risk of all-cause and cause-specific mortality among Chinese adults. This study was based on China Kadoorie Biobank (CKB). Tea consumption information was self-reported by participants at baseline. Death was mainly identified by linkage to the death registry system. Cox proportional hazard regression models estimated and 95%. With a median follow-up of 11.1 years, there were 34 661 deaths in 438 443 participants. Compared with those who never drink tea, all-cause mortality (95%) were 0.89(0.860.91) and 0.92(0.880.95) for non-daily tea drinkers and daily tea drinkers, respectively. A statistically significant difference was found in the association of tea consumption and the risk of all-cause mortality between men and women(interaction <0.05). The protective effect was mainly seen in men. Compared with those who never drink tea, daily tea drinkers had a reduced risk of death from ischemic heart disease, ischemic stroke, hemorrhagic stroke, cancer, respiration diseases and other causes of death, and the corresponding (95%) were 0.83(0.760.92), 0.82(0.690.97), 0.86(0.780.94), 1.03(0.971.09), 1.00(0.871.16), 0.84(0.780.90). Among never smokers and non-excessive drinkers, there was no statistically significant association between daily tea drinking and the risk of death from cancer. While smokers and excessive drinkers had an increased risk of death from cancer (interaction <0.001). Tea consumers had reduced risks of all-cause mortality and partial cause-specific mortality, but not for the risk of death from cancer. On the contrary, daily tea drinkers with smoking habits and excessive alcohol drinking had an increased risk of death from cancer.
为了研究中国成年人饮茶与全因死亡率及特定病因死亡率风险之间的关联。本研究基于中国嘉道理生物银行(CKB)。饮茶信息由参与者在基线时自我报告。死亡主要通过与死亡登记系统的关联来确定。Cox比例风险回归模型进行了估计并得出95%置信区间。在中位随访11.1年期间,438443名参与者中有34661人死亡。与从不饮茶者相比,非每日饮茶者和每日饮茶者的全因死亡率(95%置信区间)分别为0.89(0.86 - 0.91)和0.92(0.88 - 0.95)。在饮茶与全因死亡率风险的关联方面,男性和女性之间存在统计学显著差异(交互作用P<0.05)。保护作用主要体现在男性中。与从不饮茶者相比,每日饮茶者死于缺血性心脏病、缺血性中风、出血性中风、癌症、呼吸系统疾病和其他死因的风险降低,相应的95%置信区间分别为0.83(0.76 - 0.92)、0.82(0.69 - 0.97)、0.86(0.78 - 0.94)、1.03(0.97 - 1.09)、1.00(0.87 - 1.16)、0.84(0.78 - 0.90)。在从不吸烟者和非过量饮酒者中,每日饮茶与癌症死亡风险之间无统计学显著关联。而吸烟者和过量饮酒者癌症死亡风险增加(交互作用P<0.001)。饮茶者全因死亡率和部分特定病因死亡率风险降低,但癌症死亡风险未降低。相反,有吸烟习惯和过量饮酒的每日饮茶者癌症死亡风险增加。