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一名最初接受直肠癌治疗的患者在减压手术和放疗后转移性脊髓压迫症状得到改善。

Improvement of Metastatic Spinal Cord Compression After Decompression Surgery and Radiotherapy in a Patient Initially Treated for Rectal Cancer.

作者信息

Utsumi Nobuko, Kurosaki Hiromasa, Miura Kosei, Baba Satoshi, Koyama Yoshin

机构信息

Department of Radiation Therapy, Japan Community Healthcare Organization (JCHO) Tokyo Shinjuku Medical Center, Tokyo, JPN.

Department of Radiology and Radiation Oncology, Edogawa Hospital, Tokyo, JPN.

出版信息

Cureus. 2022 Jan 11;14(1):e21134. doi: 10.7759/cureus.21134. eCollection 2022 Jan.

DOI:10.7759/cureus.21134
PMID:35186512
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8846261/
Abstract

Many reports indicate that the prognosis of patients with rectal cancer who have thoracic spine metastases with spinal cord compression is poor. Here, we discuss a case of a patient who achieved an improvement of functional prognosis and long-term survival after undergoing surgery and radiotherapy. We report a case of a 64-year-old female who was found to have metastatic spinal cord compression (MSCC) in the second thoracic vertebra, 10 years after surgery for rectal cancer. She experienced numbness in both legs and had gait difficulties. She underwent posterior decompression surgery and radiotherapy. Her neurological symptoms improved after radiotherapy, and the patient could maintain a standing position without assistance within one week after irradiation. She has since received adjuvant chemotherapy and continues to survive five years six months since MSCC onset.

摘要

许多报告表明,患有胸椎转移并伴有脊髓压迫的直肠癌患者预后较差。在此,我们讨论一例患者,该患者在接受手术和放疗后功能预后得到改善且长期存活。我们报告一例64岁女性,她在直肠癌手术后10年被发现第二胸椎出现转移性脊髓压迫(MSCC)。她双腿麻木且行走困难。她接受了后路减压手术和放疗。放疗后其神经症状改善,放疗后一周内患者无需辅助就能保持站立姿势。此后她接受了辅助化疗,自MSCC发病后已存活五年六个月。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84a8/8846261/89c914a2ce6b/cureus-0014-00000021134-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84a8/8846261/7c8b29053a2e/cureus-0014-00000021134-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84a8/8846261/09de8e4fe054/cureus-0014-00000021134-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84a8/8846261/89c914a2ce6b/cureus-0014-00000021134-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84a8/8846261/7c8b29053a2e/cureus-0014-00000021134-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84a8/8846261/09de8e4fe054/cureus-0014-00000021134-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84a8/8846261/89c914a2ce6b/cureus-0014-00000021134-i03.jpg

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本文引用的文献

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Assessment of prognostic factors in patients with metastatic epidural spinal cord compression (MESCC) from solid tumor after surgery plus radiotherapy: a single institution experience.评估手术加放疗后来自实体瘤的转移性硬膜外脊髓压迫症(MESCC)患者的预后因素:单机构经验。
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Local disease control after decompressive surgery and adjuvant high-dose single-fraction radiosurgery for spine metastases.脊柱转移瘤减压手术后局部疾病控制和辅助高剂量单次分割放射外科治疗。
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Oligometastases and oligo-recurrence: the new era of cancer therapy.寡转移和寡复发:癌症治疗的新时代。
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