Bakhati Bibek, Sibi Victoria M, Mekala Armugam P, Ronen Joshua A, Mungara Sai S
Internal Medicine, Texas Tech University Health Sciences Center Permian Basin, Odessa, USA.
Medicine, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, RUS.
Cureus. 2022 Jan 17;14(1):e21345. doi: 10.7759/cureus.21345. eCollection 2022 Jan.
Amantadine, which is known for its antiviral activity, is presently used as therapy for Parkinson's disease. Adverse effects, such as cardiac arrhythmias, have been described in patients after ingestion of amantadine. Here, we present a patient who suffered a cardiac arrest following ingestion of a low dose of amantadine. A 71-year-old man was admitted to the emergency department for a witnessed cardiac arrest. He had developed an upper respiratory tract infection the preceding week and was prescribed 100 mg of amantadine. Within half an hour of taking the first dose, the patient collapsed. He was found to be in asystole by emergency medical services, and advanced cardiac life support protocols were initiated, including cardiopulmonary resuscitation and intubation for airway protection. However, he sustained multiple recurrences of cardiac arrest, and despite all resuscitation efforts, the patient expired.
金刚烷胺以其抗病毒活性而闻名，目前被用作帕金森病的治疗药物。摄入金刚烷胺后的患者曾出现过心律失常等不良反应。在此，我们报告一名摄入低剂量金刚烷胺后发生心脏骤停的患者。一名71岁男性因目击心脏骤停被送往急诊科。他前一周患上呼吸道感染，被开了100毫克金刚烷胺。服用首剂后半小时内，患者晕倒。紧急医疗服务人员发现他处于心搏停止状态，并启动了高级心脏生命支持方案，包括心肺复苏和气管插管以保护气道。然而，他多次复发心脏骤停，尽管进行了所有复苏努力，患者仍死亡。
