Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Heights Dermatology and Laser, Brooklyn, New York, USA.
Clin Dermatol. 2022 Jan-Feb;40(1):64-75. doi: 10.1016/j.clindermatol.2021.08.013. Epub 2021 Aug 8.
Hair loss is a common complaint that is often stressful for patients and a challenge for practitioners to treat. Fortunately, innovations in the field have contributed to growing evidence for several promising topical, oral, and light and energy-based therapies. We have reviewed the current literature about the efficacy of these treatments, including topical agents (finasteride, latanoprost, spironolactone, caffeine, and metformin), oral minoxidil, nutraceuticals, platelet-rich plasma, low-level laser therapy, fractional lasers, and laser-assisted drug delivery. In addition, several debates related to these treatments have been discussed, including post-finasteride syndrome, effects of biotin supplementation on laboratory testing, standardization of platelet-rich plasma and low-level laser therapy, and combination treatment to enhance hair transplantation.
脱发是一种常见的主诉，常给患者带来压力，也给医生的治疗带来挑战。幸运的是，该领域的创新为几种有前途的局部、口服和光与能量疗法提供了更多的证据。我们回顾了关于这些治疗方法疗效的现有文献，包括局部制剂（非那雄胺、拉坦前列素、螺内酯、咖啡因和二甲双胍）、口服米诺地尔、营养保健品、富血小板血浆、低水平激光治疗、分束激光和激光辅助药物输送。此外，还讨论了与这些治疗方法相关的几个争议，包括非那雄胺综合征、生物素补充对实验室检测的影响、富血小板血浆和低水平激光治疗的标准化以及联合治疗以增强毛发移植。
