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贫困与家庭逆境对青少年健康的影响:一项基于英国千禧队列研究的多轨迹分析

Impact of poverty and family adversity on adolescent health: a multi-trajectory analysis using the UK Millennium Cohort Study.

作者信息

Adjei Nicholas Kofi, Schlüter Daniela K, Straatmann Viviane S, Melis Gabriella, Fleming Kate M, McGovern Ruth, Howard Louise M, Kaner Eileen, Wolfe Ingrid, Taylor-Robinson David C

机构信息

Department of Public Health, Policy and Systems, University of Liverpool, Liverpool United Kingdom.

Department of Public Health Sciences, Stockholm University, Stockholm Sweden.

出版信息

Lancet Reg Health Eur. 2021 Nov 30;13:100279. doi: 10.1016/j.lanepe.2021.100279. eCollection 2022 Feb.

DOI:10.1016/j.lanepe.2021.100279
PMID:35199082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8841277/
Abstract

BACKGROUND

Children exposed to poverty and family adversities including domestic violence, parental mental ill health and parental alcohol misuse may experience poor outcomes across the life course. However, the complex interrelationships between these exposures in childhood are unclear. We therefore assessed the clustering of trajectories of household poverty and family adversities and their impacts on adolescent health outcomes.

METHODS

We used longitudinal data from the UK Millennium Cohort study on 11564 children followed to age 14 years. Family adversities included parent reported domestic violence and abuse, poor mental health and frequent alcohol use. We used a group-based multi-trajectory cluster model to identify trajectories of poverty and family adversity for children. We assessed associations of these trajectories with child physical, mental and behavioural outcomes at age 14 years using multivariable logistic regression, adjusting for confounders.

FINDINGS

Six trajectories were identified: low poverty and family adversity (43·2%), persistent parental alcohol use (7·7%), persistent domestic violence and abuse (3·4%), persistent poor parental mental health (11·9%), persistent poverty (22·6%) and persistent poverty and poor parental mental health (11·1%). Compared with children exposed to low poverty and adversity, children in the persistent adversity trajectory groups experienced worse outcomes; those exposed to persistent poor parental mental health and poverty were particularly at increased risk of socioemotional behavioural problems (adjusted odds ratio 6·4; 95% CI 5·0 - 8·3), cognitive disability (aOR 2·1; CI 1·5 - 2·8), drug experimentation (aOR 2·8; CI 1·8 - 4·2) and obesity (aOR 1·8; CI 1·3 - 2·5).

INTERPRETATION

In a contemporary UK cohort, persistent poverty and/or persistent poor parental mental health affects over four in ten children. The combination of both affects one in ten children and is strongly associated with adverse child outcomes, particularly poor child mental health.

FUNDING

The National Institute for Health Research (NIHR) Policy Research Programme, NIHR Applied Research Collaboration South London (ARC South London) at King's College Hospital NHS Foundation Trust and the Medical Research Council (MRC).

摘要

背景

经历贫困以及包括家庭暴力、父母心理健康问题和父母酗酒在内的家庭困境的儿童,在其一生可能会有不良后果。然而,童年时期这些经历之间复杂的相互关系尚不清楚。因此,我们评估了家庭贫困轨迹和家庭困境的聚类情况及其对青少年健康结果的影响。

方法

我们使用了英国千禧队列研究的纵向数据,该研究跟踪了11564名儿童至14岁。家庭困境包括家长报告的家庭暴力和虐待、心理健康不佳以及频繁饮酒。我们使用基于群体的多轨迹聚类模型来确定儿童的贫困轨迹和家庭困境轨迹。我们使用多变量逻辑回归评估这些轨迹与14岁儿童的身体、心理和行为结果之间的关联,并对混杂因素进行了调整。

研究结果

确定了六种轨迹:低贫困和家庭困境(43.2%)、父母持续酗酒(7.7%)、持续的家庭暴力和虐待(3.4%)、父母持续心理健康不佳(11.9%)、持续贫困(22.6%)以及持续贫困和父母心理健康不佳(11.1%)。与经历低贫困和困境的儿童相比,处于持续困境轨迹组的儿童有更差的结果;那些经历父母持续心理健康不佳和贫困的儿童尤其面临社会情感行为问题(调整后的优势比为6.4;95%置信区间5.0 - 8.3)、认知残疾(aOR 2.1;CI 1.5 - 2.8)、药物试验(aOR 2.8;CI 1.8 - 4.2)和肥胖(aOR 1.8;CI 1.3 - 2.5)风险的增加。

解读

在当代英国队列中,持续贫困和/或父母持续心理健康不佳影响超过十分之四的儿童。两者的结合影响十分之一的儿童,并与不良儿童结果密切相关,尤其是儿童心理健康不佳。

资金来源

国家卫生研究院(NIHR)政策研究计划、国王学院医院国民保健服务信托基金的NIHR南伦敦应用研究合作组织(ARC南伦敦)以及医学研究理事会(MRC)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffb5/8841277/c18e41d741bf/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffb5/8841277/32f8297ecd54/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffb5/8841277/ba2b0535e7f4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffb5/8841277/c18e41d741bf/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffb5/8841277/32f8297ecd54/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffb5/8841277/ba2b0535e7f4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffb5/8841277/c18e41d741bf/gr3.jpg

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本文引用的文献

1
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Int J Epidemiol. 2021 Nov 10;50(5):1628-1638. doi: 10.1093/ije/dyab099.
2
Poverty, health, and covid-19.贫困、健康与新冠疫情
BMJ. 2021 Feb 12;372:n376. doi: 10.1136/bmj.n376.
3
Adversity in childhood is linked to mental and physical health throughout life.
贫困与儿童肥胖:当前证据及未来研究方法
Curr Obes Rep. 2025 Apr 11;14(1):33. doi: 10.1007/s13679-025-00627-x.
4
Group-based trajectory modeling to describe the geographical distribution of tuberculosis notifications.基于群组的轨迹建模以描述结核病通报的地理分布。
BMC Public Health. 2025 Feb 27;25(1):797. doi: 10.1186/s12889-025-22083-x.
5
Population-level transitions in observed difficulties through childhood and adolescence.在儿童期和青少年期观察到的困难在人群层面上的转变。
Dev Psychol. 2025 Aug;61(8):1495-1515. doi: 10.1037/dev0001874. Epub 2025 Feb 27.
6
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7
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8
Identifying households with children who have complex needs: a segmentation model for integrated care systems.识别有复杂需求儿童的家庭:综合医疗系统的细分模型。
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9
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4
Understanding pathways to inequalities in child mental health: a counterfactual mediation analysis in two national birth cohorts in the UK and Denmark.理解儿童心理健康不平等的途径:英国和丹麦两个全国性出生队列的反事实中介分析。
BMJ Open. 2020 Oct 12;10(10):e040056. doi: 10.1136/bmjopen-2020-040056.
5
How do early-life adverse childhood experiences mediate the relationship between childhood socioeconomic conditions and adolescent health outcomes in the UK?在英国,童年早期不良经历如何调节童年社会经济状况与青少年健康结果之间的关系?
J Epidemiol Community Health. 2020 Nov;74(11):969-975. doi: 10.1136/jech-2020-213817. Epub 2020 Aug 27.
6
Trajectories of childhood adversity and mortality in early adulthood: a population-based cohort study.童年逆境轨迹与成年早期死亡率:基于人群的队列研究。
Lancet. 2020 Aug 15;396(10249):489-497. doi: 10.1016/S0140-6736(20)30621-8.
7
The Clustering of Adverse Childhood Experiences in the Avon Longitudinal Study of Parents and Children: Are Gender and Poverty Important?《阿冯纵向父母与子女研究中不良童年经历的聚类:性别和贫困重要吗?》
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8
Identifying typical trajectories in longitudinal data: modelling strategies and interpretations.识别纵向数据中的典型轨迹:建模策略和解释。
Eur J Epidemiol. 2020 Mar;35(3):205-222. doi: 10.1007/s10654-020-00615-6. Epub 2020 Mar 5.
9
Associations of adverse childhood experiences with educational attainment and adolescent health and the role of family and socioeconomic factors: A prospective cohort study in the UK.不良童年经历与受教育程度及青少年健康的关系,以及家庭和社会经济因素的作用:英国一项前瞻性队列研究。
PLoS Med. 2020 Mar 2;17(3):e1003031. doi: 10.1371/journal.pmed.1003031. eCollection 2020 Mar.
10
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Arch Dis Child. 2019 Nov;104(11):1049-1055. doi: 10.1136/archdischild-2018-316702. Epub 2019 Jun 11.