收治于三级医疗中心肾病科的慢性肾脏病患者的肺炎：一项描述性横断面研究。

Pneumonia in Patients with Chronic Kidney Disease Admitted to Nephrology Department of a Tertiary Care Center: A Descriptive Cross-sectional Study.

机构信息

Department of Medicine, Grande International Hospital, Dhapasi, Kathmandu, Nepal.

Department of Medicine, Hospital for Advanced Medicine and Surgery, Dhumbarahi, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2021 Oct 15;59(242):1000-1003. doi: 10.31729/jnma.7074.

DOI:10.31729/jnma.7074

PMID:35199688

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9107813/

Abstract

INTRODUCTION

Chronic Kidney Disease is an independent risk factor for pneumonia. The risk of hospitalization, Intensive Care Unit and ventilator requirement, in-hospital death is high in pneumonia patients with chronic kidney disease. This study aims to find the prevalence of pneumonia in patients with chronic kidney disease admitted to nephrology department of a tertiary care center.

METHODS

A descriptive cross-sectional study was conducted among all the hospital records of pneumonia patients with Chronic Kidney Disease admitted to the Nephrology department between April 2019 and April 2021. Ethical clearance was obtained from the Institutional Review Committee of same institute (Reference number: 0505202106). Statistical Package for the Social Sciences version 20 was used for analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.

RESULTS

Of the total 407 patients with Chronic Kidney Disease, 78 (19.1%) (95% Confidence Interval= 15.28-22.92) had pneumonia. Among the 78 pneumonia patients, 17 (21.8%) were Stage 3, 13 (16.7%) Stage 4 and 48 (61.5%) Stage 5 of chronic kidney disease. Forty Seven (60.3%) required Intensive Care Unit (ICU), 19 (24.4%) required ventilator and 22 (28.2%) of the patient expired in hospital. The most commonly isolated organisms were Severe Acute Respiratory Syndrome Coronavirus 2 which was 13 (16.6%) followed by Strepotococcus pneumoniae which was 8 (10.2%).

CONCLUSIONS

The prevalence of pneumonia in Chronic Kidney Disease was observed higher in our study compared to other studies.

摘要

简介

慢性肾脏病是肺炎的独立危险因素。患有慢性肾脏病的肺炎患者住院、入住重症监护病房和需要呼吸机、住院死亡的风险较高。本研究旨在找出在三级保健中心肾脏病科住院的慢性肾脏病患者中肺炎的患病率。

方法

对 2019 年 4 月至 2021 年 4 月间在肾脏病科住院的慢性肾脏病合并肺炎患者的所有病历进行描述性横断面研究。本研究获得了同一机构的机构审查委员会的伦理批准（参考编号：0505202106）。采用社会科学统计软件包 20 版进行分析。计算了 95%置信区间的点估计值以及二分类数据的频率和比例。

结果

在 407 例慢性肾脏病患者中，78 例（19.1%）（95%置信区间=15.28-22.92）患有肺炎。在 78 例肺炎患者中，3 期 17 例（21.8%），4 期 13 例（16.7%），5 期 48 例（61.5%）。47 例（60.3%）需要入住重症监护病房（ICU），19 例（24.4%）需要呼吸机，22 例（28.2%）患者在住院期间死亡。最常见的分离病原体是严重急性呼吸综合征冠状病毒 2，有 13 例（16.6%），其次是肺炎链球菌，有 8 例（10.2%）。