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[利用体外中性粒细胞损伤试验研究豚鼠对血液蛋白的过敏反应超敏表现]

[Study of anaphylectic hypersensitivity manifestations to blood protein in guinea pigs with using the neutrophil damage test in vitro].

作者信息

Tetdoeva M T

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Feb(2):80-2.

PMID:352049
Abstract

The paper is devoted to the study of hypersensitivity of anaphylactic type to horse serum in guinea pigs by means of neutrophil injury index in vitro. Simultaneously, for control, the same method was applied to the study of delayed hypersensitivity manifestations; for this purpose allergy to hemolytic staphylococcus was reproduced in these animals. The state of hypersensitivity of "anaphylactic type" against the foreign serum in guinea pigs was not accompanied by any enhanced blood neutrophil reactions, whereas high values of the test under study were characteristic of the process of guinea pigs sensitization with staphylococcus culture.

摘要

该论文致力于通过体外中性粒细胞损伤指数研究豚鼠对马血清的过敏型超敏反应。同时,作为对照,采用相同方法研究迟发型超敏反应表现;为此,在这些动物中复制对溶血性葡萄球菌的过敏反应。豚鼠对异种血清的“过敏型”超敏反应状态并未伴随任何血液中性粒细胞反应增强,而所研究测试的高值是豚鼠用葡萄球菌培养物致敏过程的特征。

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