McCrossin Robert
Cooroy Family Practice, Cooroy 4563, Australia.
Beerwah Family Clinic, Beerwah 4519, Australia.
Children (Basel). 2022 Feb 17;9(2):272. doi: 10.3390/children9020272.
The proportion of females whose ASD diagnosis is missed is unknown. The ratio of males to females with ASD is generally quoted as 4:1, though it is believed that there are biases preventing females from being diagnosed and that the true ratio is lower. These biases have not been clearly identified or quantified. Starting with a clinical dataset of 1711 children <18 years old, four different methods were employed in an inductive study to identify and quantify the biases and calculate the proportion of females missed. A mathematical model was constructed to compare the findings with current published data. The true male-to-female ratio appears to be 3:4. Eighty percent of females remain undiagnosed at age 18, which has serious consequences for the mental health of young women.
自闭症谱系障碍（ASD）诊断中被漏诊的女性比例尚不清楚。患有ASD的男性与女性比例通常被引用为4:1，不过人们认为存在一些偏差导致女性无法得到诊断，实际比例更低。这些偏差尚未得到明确识别或量化。从一个包含1711名18岁以下儿童的临床数据集开始，在一项归纳研究中采用了四种不同方法来识别和量化这些偏差，并计算漏诊女性的比例。构建了一个数学模型以将研究结果与当前已发表的数据进行比较。实际的男女比例似乎是3:4。80%的女性在18岁时仍未被诊断出来，这对年轻女性的心理健康产生了严重影响。
