McCrossin Robert
Cooroy Family Practice, Cooroy 4563, Australia.
Beerwah Family Clinic, Beerwah 4519, Australia.
Children (Basel). 2023 Jan 31;10(2):272. doi: 10.3390/children10020272.
It appears that up to 80% of females with autistic spectrum disorder (ASD) have not been diagnosed by the age of 18. This translates to a prevalence of about 5-6%, and if true, has serious implications for female mental health. One way of finding the true value is to use Bayes' Theorem with a comorbid condition as a more easily recognizable flag. An obvious choice is anorexia nervosa (AN), but it transpires that the proportion of women with ASD who develop AN is unknown. This study uses published data in novel ways to provide two methods of estimating a range for this variable, and gives a median value of 8.3% for AN in ASD and, with four other methods, a median prevalence of 6% for female ASD. The clinical implications of the diagnosis and management of ASD and its comorbidities are discussed and, as an example, a solution is provided for the rate of ASD in symptomatic generalized joint hypermobility. It is probable that one in six women with a mental health condition is autistic.
似乎高达80%的患有自闭症谱系障碍（ASD）的女性在18岁时未被诊断出来。这意味着患病率约为5%-6%，如果属实，将对女性心理健康产生严重影响。找到真实值的一种方法是使用贝叶斯定理，将共病情况作为更容易识别的标志。一个明显的选择是神经性厌食症（AN），但结果发现患有ASD并发展为AN的女性比例尚不清楚。本研究以新颖的方式使用已发表的数据，提供了两种估计该变量范围的方法，并给出了ASD中AN的中位数为8.3%，以及其他四种方法得出的女性ASD的中位数患病率为6%。文中讨论了ASD及其共病的诊断和管理的临床意义，并举例给出了有症状的全身关节过度活动中ASD发生率的解决方案。患有心理健康问题的女性中可能六分之一是自闭症患者。
