Fagehi Raied, El-Hiti Gamal A, Alsubaie Mushawwat H, Abusharha Ali, Alanazi Mana A, Masmali Ali M, Almubrad Turki
Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia.
Healthcare (Basel). 2022 Feb 21;10(2):405. doi: 10.3390/healthcare10020405.
Dry eye symptoms are associated with refractive errors. We aimed to measure the tear evaporation rate (TER) in subjects with refractive errors (RE) using a portable evaporimeter. This nonrandomized, case-control, and observational study included 75 subjects, including 25 subjects aged 18-38 years (28.8 ± 6.8 years) with myopia (-0.75 to -3.75 D) and 25 subjects aged 18-39 years (27.7 ± 5.5 years) with hyperopia (+0.50 to +3.75 D). In addition, a control group of 25 subjects with emmetropic eyes aged 20-30 years (23.6 ± 2.6 years) was recruited. The ocular surface disease index (OSDI) was completed, followed by the TER measurements using a portable evaporimeter. The OSDI score and TER measurements showed dry eye symptoms in 36% and 48% of myopic subjects, respectively. For hyperopic participants, dry eye was observed in 24% and 56% of the subjects based on the OSDI and TER scores, respectively. Significant differences (Mann-Whitney test; < 0.001) were found among the OSDI and TER scores recorded within the study (myopic and hyperopic subjects) and control groups. Significant strong positive correlations were detected between the OSDI and TER scores in both myopic ( = 0.004; = 0.559) and hyperopic ( = 0.001; = 0.619) subjects. The TER scores were significantly higher in subjects with RE (myopic and hyperopic) as compared with individuals with normal eyes.
干眼症状与屈光不正有关。我们旨在使用便携式蒸发仪测量屈光不正(RE)患者的泪液蒸发率(TER)。这项非随机、病例对照观察性研究纳入了75名受试者,其中包括25名年龄在18 - 38岁(平均28.8±6.8岁)的近视患者(近视度数为-0.75至-3.75 D)和25名年龄在18 - 39岁(平均27.7±5.5岁)的远视患者(远视度数为+0.50至+3.75 D)。此外,还招募了25名年龄在20 - 30岁(平均23.6±2.6岁)的正视眼受试者作为对照组。先完成眼表疾病指数(OSDI)评估,然后使用便携式蒸发仪测量TER。OSDI评分和TER测量结果显示,分别有36%和48%的近视受试者存在干眼症状。对于远视受试者,根据OSDI和TER评分,分别有24%和56%的受试者存在干眼。在研究记录的OSDI和TER评分(近视和远视受试者)与对照组之间发现了显著差异(Mann-Whitney检验;P<0.001)。在近视(P = 0.004;r = 0.559)和远视(P = 0.001;r = 0.619)受试者中,OSDI和TER评分之间均检测到显著的强正相关。与正常眼个体相比,RE(近视和远视)受试者的TER评分显著更高。