Department of Chemistry, College of Science, Al-Nahrain University, Baghdad 10072, Iraq.
The Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth SY23 3DA, UK.
Molecules. 2022 Feb 16;27(4):1338. doi: 10.3390/molecules27041338.
The absolute stereochemistry of the marine alkaloid ()-()-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH.
通过从 Fmoc-D-Dab(Boc)-OH 出发经六步反应、总收率为 15.5%的汇聚式全合成，确定了海洋生物碱 ()-()-tiruchanduramine 的绝对立体化学结构。
