Centro de Investigaciones en Optica, A. C., Loma del Bosque 115, Lomas del Campestre, 37150, Leon, Guanajuato, Mexico.
Department of Physics, Philipps-Universität Marburg, Renthof 5, 35032, Marburg, Germany.
Sci Rep. 2022 Feb 24;12(1):3110. doi: 10.1038/s41598-022-06996-w.
Diabetic foot syndrome, a long term consequence of Diabetes Mellitus, is the most common cause of non-traumatic amputations. Around 8% of the world population suffers from diabetes, 15% of diabetic patients present a diabetic foot ulcer which leads to amputation in 2.5% of the cases. There is no objective method for the early diagnosis and prevention of the syndrome and its consequences. We test terahertz imaging, which is capable of mapping the cutaneous hydration, for the evaluation of the diabetic foot deterioration as an early diagnostic test as well as ulcers prevention and tracking tool. Furthermore, the analysis of our terahertz measurements combined with neurological and vascular assessment of the patients indicates that the dehydration is mainly related to the peripheral neuropathy without a significant vascular cause.
糖尿病足综合征是糖尿病的一种长期后果，是最常见的非创伤性截肢原因。全球约有 8%的人口患有糖尿病，15%的糖尿病患者患有糖尿病足溃疡，其中 2.5%的患者会导致截肢。目前还没有客观的方法来早期诊断和预防该综合征及其后果。我们测试太赫兹成像技术，该技术能够绘制皮肤水合图，以评估糖尿病足恶化情况，作为早期诊断测试以及溃疡预防和跟踪工具。此外，我们的太赫兹测量分析结合患者的神经和血管评估表明，脱水主要与周围神经病变有关，而不是由显著的血管原因引起的。
