Department of Obstetrics and Gynecology, Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.
Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2022 Feb 15;60(246):137-141. doi: 10.31729/jnma.7221.
Metabolic syndrome in polycystic ovarian syndrome is associated with a long-term risk of developing type 2 diabetes mellitus and cardiovascular disease. This study aims to find the prevalence of metabolic syndrome among patients with polycystic ovarian syndrome presenting to a tertiary care hospital.
A descriptive cross-sectional study was done on women attending the obstetrics and gynecology outpatient department of a tertiary care hospital from June 2020 to May 2021. A total of 106 women diagnosed with polycystic ovarian syndrome using Rotterdam criteria 2003 were recruited for the study and cases of metabolic syndrome was defined according to the modified American Heart Association/National Heart Lung and Blood Institute. Ethical approval was taken from the Institutional Review Committee of Nepal Medical College and Teaching Hospital (Reference number: 001-077/078). Convenience sampling was done. The collected data was entered and analyzed in Statistical Package for the Social Sciences version 21. Calculation of point estimate at 95% confidence interval was done along with frequency and proportion for binary data.
Among 106 women with polycystic ovarian syndrome, 50 (47.1%) had metabolic syndrome (37.59-56.60 at 95% Confidence Interval). The most common component of metabolic syndrome was low high-density lipoprotein cholesterol in 90 (84.9%) followed by central obesity in 60 (56.6%), hypertriglyceridemia in 47 (44.33%), high fasting sugar in 34 (32.07%), and high blood pressure in 14 (13.2%).
The prevalence of metabolic syndrome among patients with the polycystic ovarian syndrome was similar to other studies done in similar settings.
多囊卵巢综合征中的代谢综合征与发生 2 型糖尿病和心血管疾病的长期风险相关。本研究旨在寻找在一家三级保健医院就诊的多囊卵巢综合征患者中代谢综合征的患病率。
这是一项在 2020 年 6 月至 2021 年 5 月期间于一家三级保健医院妇产科门诊就诊的女性中进行的描述性横断面研究。共招募了 106 名符合 2003 年鹿特丹标准的多囊卵巢综合征患者，并根据改良的美国心脏协会/美国国立心肺血液研究所标准来定义代谢综合征病例。本研究已获得尼泊尔医学院和教学医院机构审查委员会的伦理批准（编号：001-077/078）。采用便利抽样法。收集的数据输入并在统计软件包 21 版中进行分析。计算了 95%置信区间的点估计值，并对二项数据进行了频率和比例的计算。
在 106 名多囊卵巢综合征患者中，有 50 名（47.1%）患有代谢综合征（95%置信区间为 37.59-56.60）。代谢综合征最常见的表现是低高密度脂蛋白胆固醇（90 例，84.9%），其次是中心性肥胖（60 例，56.6%）、高三酰甘油血症（47 例，44.33%）、空腹血糖升高（34 例，32.07%）和高血压（14 例，13.2%）。
在多囊卵巢综合征患者中，代谢综合征的患病率与在类似环境中进行的其他研究相似。
