Dental and Periodontal Research Center, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Statistics and Epidemiology, Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran.
Clin Exp Dent Res. 2022 Apr;8(2):571-582. doi: 10.1002/cre2.546. Epub 2022 Feb 27.
The push-out bond strength (POBS) of calcium silicate-based cements (CSCs) to the dentinal wall is considered one of the essential physical properties for clinical success. The presence of blood in the treatment area affects the POBS of these types of cement. This study aimed to evaluate the impact of blood contamination on the bond strength of CSCs and dentinal walls.
This systematic review was performed by searching electronic databases (MEDLINE-PubMed, Scopus, and EMBASE) to include relevant in vitro studies published between 1992 and April 2020. Two reviewers independently evaluated the selected studies and extracted data on the type of studied CSCs, evaluated area of the teeth, sample size, the dimension of a prepared area, slice thickness, storage duration, the setting of the universal testing machine (UTM), effects of blood contamination on POBS of CSCs and their failure modes. The bond strength of evaluated CSCs in studies was used for network meta-analysis.
Initial searches identified 292 articles, while only 13 articles met the inclusion criteria. Full texts of these articles were evaluated, and data extraction was performed. The effect of blood contamination on bond strength to the dentinal wall was assessed in various CSCs such as PMTA, Biodentine, and AMTA. The network meta-analysis results showed that the bond strength of Biodentine was significantly higher than other types of cement in blood presence (p < .05).
Based on the current systematic review, despite controversies among the result of the different articles and the lack of data for some CSCs like bioaggregate, it could be concluded that the bond strength of Biodentine to the dentinal wall is better than other evaluated CSCs in the presence of blood.
钙硅酸钠基水泥（CSC）与牙本质壁的推出强度（POBS）被认为是临床成功的基本物理性能之一。治疗区域存在血液会影响这些类型的水泥的 POBS。本研究旨在评估血液污染对 CSC 和牙本质壁粘结强度的影响。
本系统评价通过搜索电子数据库（MEDLINE-PubMed、Scopus 和 EMBASE），纳入了 1992 年至 2020 年 4 月期间发表的相关体外研究。两名评审员独立评估了所选研究，并提取了关于研究用 CSC 类型、评估牙齿区域、样本量、预备区域尺寸、切片厚度、储存时间、万能试验机（UTM）设置、血液污染对 CSC 的 POBS 及其失效模式的影响的数据。研究中评估的 CSC 的粘结强度用于网络荟萃分析。
最初的搜索确定了 292 篇文章，而只有 13 篇文章符合纳入标准。评估了这些文章的全文，并进行了数据提取。在各种 CSC 中评估了血液污染对牙本质壁粘结强度的影响，如 PMTA、Biodentine 和 AMTA。网络荟萃分析结果表明，在存在血液的情况下，Biodentine 的粘结强度明显高于其他类型的水泥（p<0.05）。
根据目前的系统评价，尽管不同文章的结果存在争议，并且某些 CSC（如生物骨料）的数据缺乏，但可以得出结论，在存在血液的情况下，Biodentine 与牙本质壁的粘结强度优于其他评估的 CSC。
