Faculty of Health Sciences, University Marien Ngouabi, Brazzaville, Congo.
National Research Institute on Health Sciences, Brazzaville, Congo.
Afr Health Sci. 2021 Sep;21(3):1100-1106. doi: 10.4314/ahs.v21i3.18.
The global pandemic Coronavirus Disease 2019 (COVID-19) due to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is reported to be potentially severe in patients with morbid conditions. One common reported comorbidities is diabetes. We aimed in this study to precise the clinical characteristics and outcomes in a series of congolese diabetic patients affected by COVID-19 infection.
We retrospectely studied from 256 COVID-19 patients, a cohort of 30 persons with previously known diabetes. The glycaemia controls have been obtained by plasma glucose assay. All patients have been tested positive to SARS-CoV-2 by RT-PCR method.
The COVID-19 diabetic patients represented 11,7% of all COVID-19 patients with confidence interval of 95% [7,77-15,65]. Older individuals and male sex were predominent. Dyspnea and sauration of oxygen < 90 were significatives and added risk factors were noted in 63.3% of patients, particulary hyperglycaemia with hypertension or obesity. The mortality rate at the percentage of 36.7% was more prevalent in patients with added comorbidities (30%) versus without comorbidities (6.7%).
Congolese COVID-19 diabetic patients of male sex and older age exhibiting arterial hypertension and obesity are the most exposed to severe COVID-19 and increasead mortality rate.
由严重急性呼吸系统综合征冠状病毒 2 型（SARS-CoV-2）引起的全球大流行疾病 2019 年冠状病毒病（COVID-19）据报道在患有病态的患者中可能很严重。一种常见的报告合并症是糖尿病。我们旨在本研究中准确描述一系列受 COVID-19 感染影响的刚果糖尿病患者的临床特征和结局。
我们回顾性研究了 256 名 COVID-19 患者中的 30 名先前已知患有糖尿病的患者。血糖控制通过血浆葡萄糖测定获得。所有患者均通过 RT-PCR 方法检测到 SARS-CoV-2 呈阳性。
COVID-19 糖尿病患者占所有 COVID-19 患者的 11.7%，置信区间为 95% [7,77-15,65]。年龄较大的个体和男性居多。呼吸困难和血氧饱和度<90%是显著的，并且在 63.3%的患者中注意到了附加的危险因素，特别是合并高血压或肥胖症的高血糖。伴有附加合并症的患者（30%）的死亡率为 36.7%，比无合并症的患者（6.7%）更为普遍。
患有动脉高血压和肥胖症的刚果 COVID-19 糖尿病男性和老年患者最容易受到严重 COVID-19 和增加的死亡率的影响。
