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泰国药用植物提取物对鱼类病原菌的时间-杀菌动力学及抗菌活性

Time-kill kinetics and antimicrobial activities of Thai medical plant extracts against fish pathogenic bacteria.

作者信息

Techaoei Surachai

机构信息

Department of Thai Traditional Medicine, Faculty of Integrative Medicine, Rajamangala University of Technology, Thanyaburi, Pathumthani, Thailand.

出版信息

J Adv Pharm Technol Res. 2022 Jan-Mar;13(1):25-29. doi: 10.4103/japtr.japtr_241_21. Epub 2022 Jan 21.

Abstract

The main objective of this work was to conduct the microbial control of Thai herbs against fish pathogens and their time-kill kinetics activity. Ten medicinal plants were selected to test antimicrobial activity against aquatic pathogens including , sp., and sp. and extracts showed the best activity against and sp. Among them, expressed the great activity against and sp. with the test concentration of MIC values of 1.25 and 2.50 mg/mL and MBC values of 5.0 and 10.0 mg/mL, while the MIC and MBC values of were found to be 2.50 and 10.0 mg/mL with sp. The plant extracts of and at 1MIC, 2MIC, and 3MIC values really showed time-kill kinetics potential against fish pathogen on period of 3-18 h. In conclusion, plant extracts are good potentials sources as antifish pathogens and safety in an aquatic ecosystem.

摘要

这项工作的主要目的是对泰国草药进行微生物控制,以对抗鱼类病原体及其时间杀灭动力学活性。选择了10种药用植物来测试其对包括 、 种和 种在内的水生病原体的抗菌活性。 提取物对 和 种显示出最佳活性。其中, 在1.25和2.50 mg/mL的MIC值测试浓度以及5.0和10.0 mg/mL的MBC值下,对 和 种表现出很强的活性,而 对 种的MIC和MBC值分别为2.50和10.0 mg/mL。 和 的植物提取物在1MIC、2MIC和3MIC值时,在3 - 18小时的时间段内确实显示出对鱼类病原体的时间杀灭动力学潜力。总之,植物提取物作为抗鱼类病原体在水生生态系统中具有良好的潜力来源且安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4289/8820347/313393e8498f/JAPTR-13-25-g001.jpg

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