Kim Shinuk, Kang Hyunsik
Department of Smart Information Communication Engineering, Sangmyung University, Cheonan, South Korea.
College of Sport Science, Sungkyunkwan University, Suwon, South Korea.
Iran J Public Health. 2022 Jan;51(1):105-114. doi: 10.18502/ijph.v51i1.8301.
To investigate the impact of lifestyle risk factors on all-cause and cardiovascular disease (CVD) mortality in Korean women aged 60 yr and older.
Data (n = 3,034) obtained from the Korean longitudinal study of aging were analyzed. Exposures included lifestyle risk factors, such as smoking, alcohol abuse, underweight/obesity, physical inactivity, and unintentional weight loss. Primary outcomes were premature deaths from specific and all-causes.
During 9.6±2.0 yr of follow-up, there were 628 cases (20.7%) of death from all causes, of which 137 cases (4.5%) were from CVD. Compared to zero risk factor (hazard ratio, HR=1), crude HR of all-cause mortality was 2.277 (95% confidence interval, CI, 1.712 ∼ 3.030, < 0.001) for one risk factor, 2.977 (95% CI, 2.124 ∼ 4.003, < 0.001) for two risk factors, and 5.154 (95% CI, 3.515 ∼ 7.557, < 0.001) for three or more risk factors. Compared to zero risk factor (HR=1), crude HR of CVD mortality was 2.035 (95% CI, 1.422 ∼ 2.913, < 0.001) for one risk factor, 2.468 (95% CI, 1.708 ∼ 3.567, < 0.001) for two risk factor, and 4.484 (95% CI, 2.830 ∼ 7.102, < 0.001) for three or more risk factors. Adjusted HRs of all-cause ( = 0.016) and CVD ( = 0.050) for three or more risk factors only remained significant for three or more risk factors.
The current findings showed that individual and combined lifestyle risk factors were significantly associated with increased risks of all-cause and CVD mortality in older Korean women.
探讨生活方式风险因素对60岁及以上韩国女性全因死亡率和心血管疾病（CVD）死亡率的影响。
对韩国老年纵向研究获得的数据（n = 3,034）进行分析。暴露因素包括生活方式风险因素，如吸烟、酗酒、体重过轻/肥胖、缺乏身体活动和非故意体重减轻。主要结局是特定原因和全因导致的过早死亡。
在9.6±2.0年的随访期间，共有628例（20.7%）全因死亡，其中137例（4.5%）死于心血管疾病。与零风险因素（风险比，HR = 1）相比，一个风险因素的全因死亡率粗HR为2.277（95%置信区间，CI，1.712～3.030，P < 0.001），两个风险因素为2.977（95%CI，2.124～4.003，P < 0.001），三个或更多风险因素为5.154（95%CI，3.515～7.557，P < 0.001）。与零风险因素（HR = 1）相比，一个风险因素的心血管疾病死亡率粗HR为2.035（95%CI，1.422～2.913，P < 0.001），两个风险因素为2.468（95%CI，1.708～3.567，P < 0.001），三个或更多风险因素为4.484（95%CI，2.830～7.102，P < 0.001）。仅三个或更多风险因素的全因（P = 0.016）和心血管疾病（P = 0.050）调整后HR仍然显著。
目前的研究结果表明，个体和综合生活方式风险因素与老年韩国女性全因死亡率和心血管疾病死亡率增加显著相关。
