Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City.
Department of Epidemiology, University of Iowa, Iowa City.
JAMA Netw Open. 2022 Feb 1;5(2):e2148485. doi: 10.1001/jamanetworkopen.2021.48485.
Although survival for in-hospital cardiac arrest (IHCA) has improved substantially over the last 2 decades, survival rates have plateaued in recent years. A better understanding of hospital differences in IHCA incidence may provide important insights regarding best practices for prevention of IHCA.
To determine the incidence of IHCA among Medicare beneficiaries, and evaluate hospital variation in incidence of IHCA.
DESIGN, SETTING, AND PARTICIPANTS: This observational cohort study analyzes 2014 to 2017 data from 170 hospitals participating in the Get With The Guidelines-Resuscitation registry, linked to Medicare files. Participants were adults aged 65 years and older. Statistical analysis was performed from January to December 2021.
Case-mix index, teaching status, and nurse-staffing.
Hospital incidence of IHCA among Medicare beneficiaries was estimated as the number of IHCA patients divided by the total number of hospital admissions. Multivariable hierarchical regression models were used to calculate hospital incidence rates adjusted for differences in patient case-mix and evaluate the association of hospital variables with IHCA incidence.
Among a total of 4.5 million admissions at 170 hospitals, 38 630 patients experienced an IHCA during 2014 to 2017. Among the 38 630 patients with IHCAs, 7571 (19.6%) were non-Hispanic Black, 26 715 (69.2%) were non-Hispanic White, and 16 732 (43.3%) were female; the mean (SD) age at admission was 76.3 (7.8) years. The median risk-adjusted IHCA incidence was 8.5 per 1000 admissions (95% CI, 8.2-9.0 per 1000 admissions). After adjusting for differences in case-mix index, IHCA incidence varied markedly across hospitals ranging from 2.4 per 1000 admissions to 25.5 per 1000 admissions (IQR, 6.6-11.4; median odds ratio, 1.51 [95% CI, 1.44-1.58]). Among hospital variables, a higher case-mix index, higher nurse staffing, and teaching status were associated with a lower hospital incidence of IHCA.
This cohort study found that the incidence of IHCA varies markedly across hospitals, and hospitals with higher nurse staffing and teaching status had lower IHCA incidence rates. Future studies are needed to better understand processes of care at hospitals with exceptionally low IHCA incidence to identify best practices for cardiac arrest prevention.
尽管在过去的 20 年中,院内心脏骤停(IHCA)的生存率有了显著提高,但近年来生存率已趋于平稳。更好地了解医院在 IHCA 发生率方面的差异,可能为预防 IHCA 的最佳实践提供重要的见解。
确定医疗保险受益人的 IHCA 发生率,并评估医院 IHCA 发生率的差异。
设计、地点和参与者:这项观察性队列研究分析了 2014 年至 2017 年期间来自参与 Get With The Guidelines-Resuscitation 注册中心的 170 家医院的数据,该中心与医疗保险档案相关联。参与者为年龄在 65 岁及以上的成年人。统计分析于 2021 年 1 月至 12 月进行。
病例组合指数、教学地位和护士配备。
医疗保险受益人的医院 IHCA 发生率估计为 IHCA 患者人数除以医院总入院人数。使用多变量分层回归模型计算了调整患者病例组合差异后的医院发生率,并评估了医院变量与 IHCA 发生率的关系。
在 170 家医院的 450 万例住院治疗中,38630 例患者在 2014 年至 2017 年期间经历了 IHCA。在 38630 例 IHCA 患者中,7571 例(19.6%)为非西班牙裔黑人,26715 例(69.2%)为非西班牙裔白人,16732 例(43.3%)为女性;入院时的平均(SD)年龄为 76.3(7.8)岁。经风险调整后的 IHCA 发生率中位数为每 1000 例住院患者 8.5 例(95%CI,每 1000 例住院患者 8.2-9.0 例)。在调整病例组合指数差异后,医院之间 IHCA 的发生率差异显著,从每 1000 例住院患者 2.4 例到每 1000 例住院患者 25.5 例(IQR,6.6-11.4;中位数优势比,1.51[95%CI,1.44-1.58])。在医院变量中,较高的病例组合指数、较高的护士配备和教学地位与较低的医院 IHCA 发生率相关。
这项队列研究发现,IHCA 的发生率在医院之间差异显著,护士配备和教学地位较高的医院 IHCA 发生率较低。未来需要进一步研究,以更好地了解 IHCA 发生率极低的医院的护理流程,从而确定预防心脏骤停的最佳实践。